Results 121 to 130 of about 360,849 (311)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Dataflow modeling for reconfigurable signal processing systems [PDF]

, 2018
Nowadays, adaptive signal processing systems have become a reality. Their development has been mainly driven by the need of satisfying diverging constraints and changeable user needs, like resolution and throughput versus energy consumption.
Desnos K., Palumbo F.
core   +1 more source

Development of FPGA-Based Data Acquisition System for Metallic Magnetic Calorimeter

Journal of Isotopes
Metallic magnetic calorimeters are a class of low-temperature particle detectors based on calorimetry，utilizing metallic paramagnetic temperature sensors to convert the temperature rise of an absorber upon the absorption of incident particle energy into ...
Yang LI, Lijun XU, Yuntao LIU, Baoji ZHU, Yuhe ZHANG, Qi JIN, Zongzheng ZHOU, Yuanqiao LI, Min LIN, Lijie HAO, Hongliang WANG, Shichun JIN   +11 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

An Integrated Approach to Energy Harvester Modeling and Performance Optimization [PDF]

, 2007
This paper proposes an integrated approach to energy harvester (EH) modeling and performance optimization where the complete mixed physical-domain EH (micro generator, voltage booster, storage element and load) can be modeled and optimized.
Beeby, Steve, Torah, Russel, Wang, Leran, Bashir M. Al-Hashimi, Kazmierski, Tom, Al-Hashimi, Bashir, Steve P. Beeby, Leran Wang, Tom J. Kazmierski, Russel N. Torah   +9 more
core   +1 more source

Linear optical wave energy redistribution methods for photonic signal processing

npj Nanophotonics
Manipulating the phase of an optical wave over time and frequency gives full control to the user to implement a wide variety of energy preserving transformations directly in the analogue optical domain. These can be achieved using widely available linear
Connor Rowe, Xinyi Zhu, Benjamin Crockett, Geunweon Lim, Majid Goodarzi, Manuel Fernández, James van Howe, Hao Sun, Saket Kaushal, Afsaneh Shoeib, José Azaña   +10 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Energy Stealth Evaluation of Radar Systems with a Space–Time Modulated Probing Signal

Известия высших учебных заведений России: Радиоэлектроника
Introduction. Increased attention is currently paid to the issues of stealth operation of various radar systems. The article considers the possibility of increasing the energy stealth of a radar system with a complex quasi-continuous signal due to ...
V. M. Kutuzov, V. P. Ipatov, S. S. Sokolov   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The application of advanced signal processing techniques to the condition monitoring of electrical machine drive systems [PDF]

, 2007
Includes bibliographical references (leaves 128-129).The thesis examines the use of two time-frequency domain signal processing tools in its application to condition monitoring of electrical machine drive systems.
Barendse, Paul Stanley
core