Results 121 to 130 of about 3,640,313 (369)

Quality-Aware Signal Processing Mechanism of PPG Signal for Long-Term Heart Rate Monitoring

open access: yesSensors
Photoplethysmography (PPG) is widely utilized in wearable healthcare devices due to its convenient measurement capabilities. However, the unrestricted behavior of users often introduces artifacts into the PPG signal.
Win-Ken Beh, Yu-Chia Yang, An-Yeu Wu
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Development of FPGA-Based Data Acquisition System for Metallic Magnetic Calorimeter

open access: yesJournal of Isotopes
Metallic magnetic calorimeters are a class of low-temperature particle detectors based on calorimetry,utilizing metallic paramagnetic temperature sensors to convert the temperature rise of an absorber upon the absorption of incident particle energy into ...
Yang LI   +11 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Energy Stealth Evaluation of Radar Systems with a Space–Time Modulated Probing Signal

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника
Introduction. Increased attention is currently paid to the issues of stealth operation of various radar systems. The article considers the possibility of increasing the energy stealth of a radar system with a complex quasi-continuous signal due to ...
V. M. Kutuzov   +2 more
doaj   +1 more source

SIGNAL SHAPE RECOVER BY BISPECTRUM IN NOISE ENVIRONMENT

open access: yesРадіоелектронні і комп'ютерні системи, 2019
In a number of practical applications of digital signal processing, the process under study may include correlated spectral components or phase coupling.
Виктория Владимировна Науменко   +3 more
doaj   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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