Results 101 to 110 of about 10,533,673 (391)
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Green energy and steel imports reduce Europe’s net-zero infrastructure needs
Importing renewable energy to Europe may offer many potential benefits, including reduced energy costs, lower pressure on infrastructure development, and less land use within Europe.
Fabian Neumann +2 more
doaj +1 more source
Rescaling the nonadditivity parameter in Tsallis thermostatistics
The paper introduces nonadditivity parameter transformation group induced by Tsallis entropy. We discuss simple physical applications of a system in the contact with finite heat bath or with temperature fluctuations.
Korbel, Jan
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
On the means, costs, and system-level impacts of 24/7 carbon-free energy procurement
A growing number of public and private energy buyers are interested in 24/7 carbon-free energy (CFE) procurement, which means that every kilowatt-hour of electricity consumption is met by carbon-free sources at all times. It has the potential to overcome
Iegor Riepin, Tom Brown
doaj +1 more source
The great transformation: decarbonising Europeâ??s energy and transport systems [PDF]
The euro-area crisis dominates the economic news. Yet, the world and Europe may face even more important challenges that will shape our lives and the lives of our children.World population is projected to increase to 9 billion or more by 2050.
Anta Ndoye +6 more
core +1 more source
Poland’s energy security during the transformation process in comparison with the EU countries [PDF]
Anna Bluszcz +3 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Accelerating the transition from coal to renewables in Indonesia to achieve a net‐zero energy system
Historically heavily reliant on coal, Indonesia is at a crucial juncture to accelerate its transition to renewable energy in order to meet its net‐zero goals.
Ashish Gulagi +8 more
doaj +1 more source
The article addresses the issue of the foundations of the idea of energy security at the global, continental and national levels, as well as the energy transformation necessary to achieve it, which is important for the modern world – both in terms of its
Marina L. Zelenkevich +1 more
doaj +1 more source

