Results 61 to 70 of about 56,471 (208)
Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention [PDF]
, 2017 The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the hallmarks of cancer.
Carrillo, Paloma +7 more
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Fraternidad política y enfermedades raras
Araucaria, 2021 sumen Las enfermedades raras reciben, en general, menos financiación para su investigación y tratamientos médicos que el resto de enfermedades. Al margen de explicaciones científicas y económicas conocidas, existen dos grandes posiciones éticas respecto a este hecho, la que lo aprueba por razones de ética utilitarista, y la que lo condena insistiendo ...
openaire +5 more sources
AI‐assisted basal cell carcinoma diagnosis with LC‐OCT: A multicentric retrospective study
Journal of the European Academy of Dermatology and Venereology, EarlyView.Real‐time AI assistance significantly improves dermatologists' performance in diagnosing basal cell carcinoma with LC‐OCT, outperforming traditional imaging methods. AI‐assisted novices reached expert‐level performance, bridging a 2‐year expertise gap, thus supporting a broader clinical adoption of non‐invasive technologies, reducing the need for ...
Sébastien Fischman +64 more
wiley +1 more source
Anales de Pediatría (English Edition), 2020 Introduction: Congenital heart defects (CHDs) are the most prevalent and severe type of major congenital anomalies (CAs). The objective of this study was to determine the frequency and distribution of CHDs in the Valencian Region from 2007 to 2014 ...
María Pastor-García +4 more
doaj +1 more source
Interplay between glucose and palmitate uptake in breast carcinoma in vitro [PDF]
, 2018 One of the most studied tumor cells lines in vitro is the breast carcinoma MDA-MB-231 cell line. Several studies have proved its glycolytic profile, namely known as the Warburg effect.
Carrillo, Paloma +4 more
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Online communication of patients with rare diseases in Spain [PDF]
, 2015 Introducción: Este estudio se centra en la estrategia de comunicación de las organizaciones de pacientes con enfermedades raras en internet. Objetivo: Analizar la utilización de las herramientas de comunicación en internet.
Carretón-Ballester, Carmen +2 more
core +3 more sources
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 285-295, February 2026.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Orphanet Journal of Rare DiseasesBackground The low prevalence of rare diseases poses a significant challenge in advancing their understanding. This study aims to delineate the clinical and genetic characteristics of patients with rare eye diseases (RED) enrolled in the Spanish Rare ...
Alberto Lopez-de la Rosa +6 more
doaj +1 more source
Scientific Reports, 2021 High-throughput gene expression analysis is widely used. However, analysis is not straightforward. Multiple approaches should be applied and methods to combine their results implemented and investigated.
Fernando M. Jabato +9 more
doaj +1 more source
Screening of Synergic Interactions of Anti-Angiogenic and Anti-Tumor Compounds [PDF]
, 2015 Solid cancers have several common characteristics that Hanahan & Weinberg named as the hallmarks of cancer. Angiogenesis is an essential hallmark of cancer because tumor cells need oxygen and nutrients delivered by the vascular system.
García-Vilas García, Javier Alejandro +2 more
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