Results 81 to 90 of about 181,707 (268)
Suicide gene therapy targeting ewing sarcoma via an ewing-specific GGAA promoter
Scientific ReportsWe recently demonstrated that GGAA promoters (GGAAprom) can be used to drive the expression of therapeutic genes (i.e., Cas9) in vitro and in vivo in a highly specific way in Ewing sarcoma cells.
Saint T. Cervera +4 more
doaj +1 more source
Chitin-challenged Mice Model to Study M2 Macrophages Polarization
Bio-Protocol, 2015 Chitin is a key component of insects, fungi, and house-dust mites. Chitin has been shown to induce M2-type immune responses in vivo. Intranasal or intraperitoneal (i.p.) administration of chitin particles results in infiltration of eosinophils to the ...
Lidia Jiménez-García +3 more
doaj +1 more source
Revista Española de Discapacidad, 2013 Bañón Hernández, A.M. y Fornieles Alcaraz, J. (2013): “Internacionalización, formación y análisis de la realidad. Tres conceptos esenciales en el desarrollo de acciones positivas por parte de FEDER (Federación Española de Enfermedades Raras)”.
Antonio M. Bañón Hernández +1 more
doaj
Fasentin, a glucose uptake inhibitor, is also able to inhibit angiogenesis [PDF]
, 2017 Es comunicación a congreso en formato pósterThe role of glucose on endothelial cell (EC) metabolism and angiogenesis has been an emerging issue in the last few years.
Carrillo, Paloma +4 more
core
Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi +20 more
wiley +1 more source
Fraternidad política y enfermedades raras
Araucaria, 2021 sumen Las enfermedades raras reciben, en general, menos financiación para su investigación y tratamientos médicos que el resto de enfermedades. Al margen de explicaciones científicas y económicas conocidas, existen dos grandes posiciones éticas respecto a este hecho, la que lo aprueba por razones de ética utilitarista, y la que lo condena insistiendo ...
openaire +5 more sources
AI‐assisted basal cell carcinoma diagnosis with LC‐OCT: A multicentric retrospective study
Journal of the European Academy of Dermatology and Venereology, EarlyView.Real‐time AI assistance significantly improves dermatologists' performance in diagnosing basal cell carcinoma with LC‐OCT, outperforming traditional imaging methods. AI‐assisted novices reached expert‐level performance, bridging a 2‐year expertise gap, thus supporting a broader clinical adoption of non‐invasive technologies, reducing the need for ...
Sébastien Fischman +64 more
wiley +1 more source
Anales de Pediatría (English Edition), 2020 Introduction: Congenital heart defects (CHDs) are the most prevalent and severe type of major congenital anomalies (CAs). The objective of this study was to determine the frequency and distribution of CHDs in the Valencian Region from 2007 to 2014 ...
María Pastor-García +4 more
doaj +1 more source
Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention [PDF]
, 2017 The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the hallmarks of cancer.
Carrillo, Paloma +7 more
core
Atlas de enfermedades raras y fantásticas de la piel. Cuentos de amor, terror, piel y uñas
En este Atlas te sumergirás en un viaje ambivalente entre el horror de las enfermedades raras y la maravilla de las fantásticas expresiones literarias que, a través de su exquisita genialidad, nos entrega nuestro autor y provocan la estimulación ...
Adameck Abraham Hernández Collazo +1 more
semanticscholar +1 more source