Results 11 to 20 of about 12,081 (264)
Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke. [PDF]
Downregulation of H19 enhances angiogenesis and mitigates BBB damage by regulating IMP2, thereby alleviating cerebral I/R injury. Abstract Aims This study aimed to explore the effects of long noncoding RNA (lncRNA) H19 knockdown on angiogenesis and blood–brain barrier (BBB) integrity following cerebral ischemia/reperfusion (I/R) and elucidate their ...
Zhong L+9 more
europepmc +2 more sources
The aim of this work is to analyze the health hazards of enflurane exposure and to analyze the occupational exposure limits (OEL). The method of obtaining evidence based on a review of online databases of scientific journals was used.
Małgorzata Kupczewska-Dobecka
doaj +1 more source
Influence of Halogenated Hydroxyl-Alkanes Inhalation Anesthetic on the Determination of Ethanol Content in Blood [PDF]
Objective To study the influence of halogenated hydroxyl-alkanes inhalation anesthetic on the determination of ethanol content in blood. Methods Halogenated hydroxyl-alkanes were analyzed by headspace gas chromatography with double column confirmatory ...
XIE Bing , YAN Wen- jing, MENG Xian- yue, et al.
doaj +1 more source
Vecuronium-induced Neuromuscular Blockade during Enflurane, Isoflurane, and Halothane Anesthesia in Humans [PDF]
To determine the effect of the commonly used volatile anesthetics on a vecuronium-induced neuromuscular blockade, the authors studied 54 patients anesthetized with 1.2 MAC or 2.2 MAC enflurane, isoflurane, or halothane (MAC value includes contribution ...
Stephen M. Rupp+2 more
openalex +2 more sources
Aims To investigate the pharmacokinetics and safety of prolonged paracetamol use (>72 h) for neonatal pain. Methods Neonates were included if they received paracetamol orally or intravenously for pain treatment. A total of 126 samples were collected. Alanine aminotransferase and bilirubin were measured as surrogate liver safety markers. Paracetamol and
Sissel Haslund‐Krog+12 more
wiley +1 more source
Effects of N2O elimination on the elimination of second gases in a two‐step mathematical model of heterogeneous gas exchange. Abstract We have investigated the elimination of inert gases in the lung during the elimination of nitrous oxide (N2O) using a two‐step mathematical model that allows the contribution from net gas volume expansion, which occurs ...
Ben Korman+2 more
wiley +1 more source
Abstract Background and aims Cocaine use disorder (CUD) is a significant public health issue for which there is no Food and Drug Administration (FDA) approved medication. Drug repurposing looks for new cost‐effective uses of approved drugs. This study presents an integrated strategy to identify repurposed FDA‐approved drugs for CUD treatment.
Zhenxiang Gao+6 more
wiley +1 more source
We present a novel model of combined perfusion and decellularization of heart‐lung organ‐blocs in a modified Langendorff circuit. Combined heart‐lungs organ blocs retrieved from rats were successfully decellularized to create an acellular scaffold with preserved extracellular matrix to provide a bioartificial platform for combined heart and lung tissue
Alina Zubarevich+6 more
wiley +1 more source
Three days’ RIPC mitigates I/R injury by decreasing the induction of JAK2/STAT3 pathway and cell cycle regulators cyclin D1 and CDK6 by MCAO, and this net inhibition of cell cycle re‐entry by RIPC is associated with downregulation of STAT3 phosphorylation. Abstract Aims Remote ischemic pre‐conditioning (RIPC) protects against ischemia/reperfusion (I/R)
Yongmei Zhao+13 more
wiley +1 more source