Results 11 to 20 of about 12,081 (264)

ENFLURANE AND HALOTHANE [PDF]

open access: bronzeAnesthesiology, 1979
T. K. Abboud   +5 more
openalex   +3 more sources

Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke. [PDF]

open access: yesCNS Neurosci Ther
Downregulation of H19 enhances angiogenesis and mitigates BBB damage by regulating IMP2, thereby alleviating cerebral I/R injury. Abstract Aims This study aimed to explore the effects of long noncoding RNA (lncRNA) H19 knockdown on angiogenesis and blood–brain barrier (BBB) integrity following cerebral ischemia/reperfusion (I/R) and elucidate their ...
Zhong L   +9 more
europepmc   +2 more sources

Health hazards resulting from occupational exposure to enfluran – overview of tests and analysis of admissible concentration values

open access: yesMedycyna Pracy, 2022
The aim of this work is to analyze the health hazards of enflurane exposure and to analyze the occupational exposure limits (OEL). The method of obtaining evidence based on a review of online databases of scientific journals was used.
Małgorzata Kupczewska-Dobecka
doaj   +1 more source

Influence of Halogenated Hydroxyl-Alkanes Inhalation Anesthetic on the Determination of Ethanol Content in Blood [PDF]

open access: yesFayixue Zazhi, 2020
Objective To study the influence of halogenated hydroxyl-alkanes inhalation anesthetic on the determination of ethanol content in blood. Methods Halogenated hydroxyl-alkanes were analyzed by headspace gas chromatography with double column confirmatory ...
XIE Bing , YAN Wen- jing, MENG Xian- yue, et al.
doaj   +1 more source

Vecuronium-induced Neuromuscular Blockade during Enflurane, Isoflurane, and Halothane Anesthesia in Humans [PDF]

open access: bronzeAnesthesiology, 1984
To determine the effect of the commonly used volatile anesthetics on a vecuronium-induced neuromuscular blockade, the authors studied 54 patients anesthetized with 1.2 MAC or 2.2 MAC enflurane, isoflurane, or halothane (MAC value includes contribution ...
Stephen M. Rupp   +2 more
openalex   +2 more sources

Pharmacokinetics and safety of prolonged paracetamol treatment in neonates: An interventional cohort study

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 11, Page 3421-3431, November 2023., 2023
Aims To investigate the pharmacokinetics and safety of prolonged paracetamol use (>72 h) for neonatal pain. Methods Neonates were included if they received paracetamol orally or intravenously for pain treatment. A total of 126 samples were collected. Alanine aminotransferase and bilirubin were measured as surrogate liver safety markers. Paracetamol and
Sissel Haslund‐Krog   +12 more
wiley   +1 more source

Effects of N2O elimination on the elimination of second gases in a two‐step mathematical model of heterogeneous gas exchange

open access: yesPhysiological Reports, Volume 11, Issue 21, November 2023., 2023
Effects of N2O elimination on the elimination of second gases in a two‐step mathematical model of heterogeneous gas exchange. Abstract We have investigated the elimination of inert gases in the lung during the elimination of nitrous oxide (N2O) using a two‐step mathematical model that allows the contribution from net gas volume expansion, which occurs ...
Ben Korman   +2 more
wiley   +1 more source

Repurposing ketamine to treat cocaine use disorder: integration of artificial intelligence‐based prediction, expert evaluation, clinical corroboration and mechanism of action analyses

open access: yesAddiction, Volume 118, Issue 7, Page 1307-1319, July 2023., 2023
Abstract Background and aims Cocaine use disorder (CUD) is a significant public health issue for which there is no Food and Drug Administration (FDA) approved medication. Drug repurposing looks for new cost‐effective uses of approved drugs. This study presents an integrated strategy to identify repurposed FDA‐approved drugs for CUD treatment.
Zhenxiang Gao   +6 more
wiley   +1 more source

Development and evaluation of a novel combined perfusion decellularization heart‐lung model for tissue engineering of bioartificial heart‐lung scaffolds

open access: yesArtificial Organs, Volume 47, Issue 3, Page 481-489, March 2023., 2023
We present a novel model of combined perfusion and decellularization of heart‐lung organ‐blocs in a modified Langendorff circuit. Combined heart‐lungs organ blocs retrieved from rats were successfully decellularized to create an acellular scaffold with preserved extracellular matrix to provide a bioartificial platform for combined heart and lung tissue
Alina Zubarevich   +6 more
wiley   +1 more source

Inhibition of the JAK2/STAT3 pathway and cell cycle re‐entry contribute to the protective effect of remote ischemic pre‐conditioning of rat hindlimbs on cerebral ischemia/reperfusion injury

open access: yesCNS Neuroscience &Therapeutics, Volume 29, Issue 3, Page 866-877, March 2023., 2023
Three days’ RIPC mitigates I/R injury by decreasing the induction of JAK2/STAT3 pathway and cell cycle regulators cyclin D1 and CDK6 by MCAO, and this net inhibition of cell cycle re‐entry by RIPC is associated with downregulation of STAT3 phosphorylation. Abstract Aims Remote ischemic pre‐conditioning (RIPC) protects against ischemia/reperfusion (I/R)
Yongmei Zhao   +13 more
wiley   +1 more source

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