Results 21 to 30 of about 12,081 (264)

High Kinetic Energy Ion Mobility Spectrometry- Mass Spectrometry investigations of four inhalation anaesthetics : isoflurane, enflurane, sevoflurane and desflurane [PDF]

, 2022
Here we report the first High Kinetic Energy-Ion Mobility Spectrometry-Mass Spectrometric (HiKE-IMSMS) investigations involving four fluranes; isoflurane, enflurane, sevoflurane and desflurane.
Eiceman, Gary, Maerk, Tilmann, Mayhew, Chris A., Ruzsanyi, Veronika, Schaefer, Christoph, Weiss, Florentin, Zimmermann, Stefan   +6 more
core   +1 more source

Fentanyl‐induced muscle rigidity in a dog during weaning from mechanical ventilation after emergency abdominal surgery: A case report

Veterinary Medicine and Science, Volume 9, Issue 1, Page 37-42, January 2023., 2023
Jaw stiffness and apnoea in a dog with muscle rigidity during recovery from fentanyl‐ and sevoflurane‐based general anaesthesia for emergency abdominal surgery. Abstract A 22.5‐kg, 8.4‐year‐old female mixed breed dog was presented for an emergency ovariohysterectomy for pyometra.
Kazumasu Sasaki, Roberto Rabozzi, Shinya Kasai, Kazutaka Ikeda, Tatsuya Ishikawa   +4 more
wiley   +1 more source

TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β‐catenin signalling

British Journal of Pharmacology, Volume 180, Issue 2, Page 235-251, January 2023., 2023
Abstract Background and Purpose Transient receptor potential melastatin type‐8 (TRPM8) is a cold‐sensitive cation channel protein belonging to the TRP superfamily of ion channels. Here, we reveal the molecular mechanism of TRPM8 and its clinical relevance in colorectal cancer (CRC).
Ester Pagano, Barbara Romano, Donatella Cicia, Fabio A. Iannotti, Tommaso Venneri, Giuseppe Lucariello, Maria Francesca Nanì, Fabio Cattaneo, Paola De Cicco, Maria D'Armiento, Marcello De Luca, Ruggiero Lionetti, Stefania Lama, Paola Stiuso, Pietro Zoppoli, Geppino Falco, Silvia Marchianò, Stefano Fiorucci, Raffaele Capasso, Vincenzo Di Marzo, Francesca Borrelli, Angelo A. Izzo   +21 more
wiley   +1 more source

Abdominal Aortic Occlusion and the Inflammatory Effects in Heart and Brain

Mediators of Inflammation, Volume 2023, Issue 1, 2023., 2023
Background. Abdominal aortic occlusion (AAO) occurs frequently and causes ischemia/reperfusion (I/R) injury to distant organs. In this study, we aimed to investigate whether AAO induced I/R injury and subsequent damage in cardiac and neurologic tissue.
Jun Xu, Sijie Li, Alexandra Wehbe, Xunming Ji, Yong Yang, Yu Yang, Linhui Qin, Feng-Yong Liu, Yuchuan Ding, Changhong Ren, Feng Zhang   +10 more
wiley   +1 more source

Lumbrokinase, a Fibrinolytic Enzyme, Prevents Intra‐Abdominal Adhesion by Inhibiting the Migrative and Adhesive Activities of Fibroblast via Attenuation of the AP‐1/ICAM‐1 Signaling Pathway

BioMed Research International, Volume 2023, Issue 1, 2023., 2023
Intra‐abdominal adhesion is a complication following abdominal surgery caused by the suppression of fibrinolytic activity and aggravated fibroblast invasion of the injured area, which may lead to chronic illnesses such as chronic pain, intestinal obstruction, and female infertility.
Que Thanh Thanh Nguyen, Hyemin Rhee, Mikyung Kim, Moo Yeol Lee, Eun-Ju Lee, Anna Chiarini   +5 more
wiley   +1 more source

Perbandingan antara Sevofluran dan Enfluran terhadap Kontraksi Uterus, Jumlah Perdarahan, dan Skor APGAR pada Seksio Sesarea Elektif

Jurnal Anestesi Perioperatif, 2015
Different volatile agents with different physicochemical properties affect uterine contraction, amount of bleeding, and APGAR score in different ways. The objective of this study was to evaluate the effects of different volatile agents, i.e., sevoflurane
RR. Pramada Resvita, Ike Sri Redjeki, Tatang Bisri   +2 more
doaj   +1 more source

How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper

British Journal of Clinical Pharmacology, Volume 88, Issue 12, Page 5017-5033, December 2022., 2022
The safety and efficacy of pharmacotherapy in children, particularly preterms, neonates and infants, is limited by a paucity of good‐quality data from prospective clinical drug trials. A specific challenge is the establishment of valid biomarkers. OMICs technologies may support these efforts by complementary information about targeted and nontargeted ...
Eva Neumann, Filippa Schreeck, Jethro Herberg, Evelyne Jacqz Aigrain, Anke H. Maitland‐van der Zee, Antonio Pérez‐Martínez, Daniel B. Hawcutt, Elke Schaeffeler, Anders Rane, Saskia N. de Wildt, Matthias Schwab   +10 more
wiley   +1 more source

A Comparative Study of Cell Specific Effects of Systemic and Volatile Anesthetics on Identified Motor Neurons and Interneurons of Lymnaea stagnalis (L.), Both in the Isolated Brain and in Single Cell Culture

Frontiers in Physiology, 2019
1. A comparative descriptive analysis of systemic (sodium pentobarbital, sodium thiopentone, ketamine) and volatile (halothane, isoflurane, enflurane) general anesthetics revealed important differences in the neuronal responses of identified motor ...
Hadi Fathi Moghadam, Talay Yar, Munir M. Qazzaz, Ibrahim Abdelrazig Ahmed, William Winlow, William Winlow, William Winlow   +6 more
doaj   +1 more source

A novel severe cerebral venous thrombosis rat model based on semi‐ligation combined with ferric chloride and thrombin

CNS Neuroscience &Therapeutics, Volume 28, Issue 12, Page 2129-2140, December 2022., 2022
Semi‐ligation combined with ferric chloride and thrombin can serve to produce a severe and stable CVST model with multiple venous sinuses involvement, and heavy thrombus load. Inflammation may be involved in the pathophysiology of severe CVST. Abstract Aims An applicable cerebral venous sinus thrombosis (CVST) model is imperative for exploring its ...
Lipo Xiao, Xunming Ji, Haiping Zhao, Yumin Luo, Shuyuan Hu, Tingyu Zhao, Zeliang Hu, Jiangang Duan   +7 more
wiley   +1 more source

Alterações transitórias do exame neurológico durante o despertar da anestesia com enflurano, isoflurano ou sevoflurano Alteraciones transitorias del examen neurológico durante el despertar de la anestesia con enflurano, isoflurano o sevoflurano Transient neurological changes during emergence from enflurane, isoflurane or sevoflurane anesthesia

Revista Brasileira de Anestesiologia, 2001
JUSTIFICATIVA E OBJETIVOS: Anormalidades transitórias do exame neurológico ocorrem durante o despertar da anestesia com halotano, enflurano e isoflurano.
Luiz Fernando Soares, Pablo Escovedo Helayel, Getúlio Rodrigues de Oliveira Filho, Rogério do Amaral   +3 more
doaj   +1 more source