Results 21 to 30 of about 12,838 (283)

Effects of maternal enflurane exposure on NR2B expression in the hippocampus of their offspring

Brazilian Journal of Pharmaceutical Sciences, 2015
This work aims to study the pathogenesis of learning and memory impairment in offspring rats resulting from maternal enflurane anesthesia by focusing on the expression of the N-methyl-d-aspartic acid receptor subunit 2B (NR2B) in the hippocampus of the ...
Fo-Quan Luo, Jun-Wu Liu, Shu-Xin Tang, Wei-Lu Zhao, Yan Hu, Lin Xu, Meng-Yuan Li   +6 more
doaj   +1 more source

Inhibition of the JAK2/STAT3 pathway and cell cycle re‐entry contribute to the protective effect of remote ischemic pre‐conditioning of rat hindlimbs on cerebral ischemia/reperfusion injury

CNS Neuroscience &Therapeutics, Volume 29, Issue 3, Page 866-877, March 2023., 2023
Three days’ RIPC mitigates I/R injury by decreasing the induction of JAK2/STAT3 pathway and cell cycle regulators cyclin D1 and CDK6 by MCAO, and this net inhibition of cell cycle re‐entry by RIPC is associated with downregulation of STAT3 phosphorylation. Abstract Aims Remote ischemic pre‐conditioning (RIPC) protects against ischemia/reperfusion (I/R)
Yongmei Zhao, Mao Ding, Feng Yan, Jie Yin, Wenjuan Shi, Nan Yang, Haiping Zhao, Yalan Fang, Yuyou Huang, Yangmin Zheng, Xueqi Yang, Wei Li, Xunming Ji, Yumin Luo   +13 more
wiley   +1 more source

A Comparative Study of Cell Specific Effects of Systemic and Volatile Anesthetics on Identified Motor Neurons and Interneurons of Lymnaea stagnalis (L.), Both in the Isolated Brain and in Single Cell Culture

Frontiers in Physiology, 2019
1. A comparative descriptive analysis of systemic (sodium pentobarbital, sodium thiopentone, ketamine) and volatile (halothane, isoflurane, enflurane) general anesthetics revealed important differences in the neuronal responses of identified motor ...
Hadi Fathi Moghadam, Talay Yar, Munir M. Qazzaz, Ibrahim Abdelrazig Ahmed, William Winlow, William Winlow, William Winlow   +6 more
doaj   +1 more source

Fentanyl‐induced muscle rigidity in a dog during weaning from mechanical ventilation after emergency abdominal surgery: A case report

Veterinary Medicine and Science, Volume 9, Issue 1, Page 37-42, January 2023., 2023
Jaw stiffness and apnoea in a dog with muscle rigidity during recovery from fentanyl‐ and sevoflurane‐based general anaesthesia for emergency abdominal surgery. Abstract A 22.5‐kg, 8.4‐year‐old female mixed breed dog was presented for an emergency ovariohysterectomy for pyometra.
Kazumasu Sasaki, Roberto Rabozzi, Shinya Kasai, Kazutaka Ikeda, Tatsuya Ishikawa   +4 more
wiley   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

Alterações transitórias do exame neurológico durante o despertar da anestesia com enflurano, isoflurano ou sevoflurano Alteraciones transitorias del examen neurológico durante el despertar de la anestesia con enflurano, isoflurano o sevoflurano Transient neurological changes during emergence from enflurane, isoflurane or sevoflurane anesthesia

Revista Brasileira de Anestesiologia, 2001
JUSTIFICATIVA E OBJETIVOS: Anormalidades transitórias do exame neurológico ocorrem durante o despertar da anestesia com halotano, enflurano e isoflurano.
Luiz Fernando Soares, Pablo Escovedo Helayel, Getúlio Rodrigues de Oliveira Filho, Rogério do Amaral   +3 more
doaj   +1 more source

Synthesis of 2-Methyl-3-indolylacetic Derivatives as Anti-Inflammatory Agents That Inhibit Preferentially Cyclooxygenase 1 without Gastric Damage [PDF]

, 2006
Novel substituted 2-methyl-3-indolylacetic derivatives were synthesized and evaluated for their activity in vitro and in vivo on COX-1 and COX-2. Active compounds were screened to determine their gastrointestinal tolerability in vivo in the rat.
C. Renner, CALIENDO, GIUSEPPE, CIRINO, GIUSEPPE, FIORINO, FERDINANDO, PERISSUTTI, ELISA, ROSSI, ANTONIETTA, ROVIEZZO, FIORENTINA, SANTAGADA, VINCENZO, SAUTEBIN, LIDIA, SEVERINO, BEATRICE   +9 more
core   +1 more source

Is Enflurane Hepatotoxic?

Anesthesia & Analgesia, 1986
We evaluated 88 cases of hepatic injury that followed, and were attributed to, enflurane anesthesia. In 30 of the cases, data were insufficient to assess the role of enflurane vs other variables as causal factors. In 43 ("unlikely") patients, factors known to produce hepatic injury were clearly present; in the remaining 15 ("possible"), such factors ...
Linda D. Ferrell, Edmond I. Eger, Smuckler Ea, Brynte H. Johnson, Charles H. Goldsmith   +4 more
openaire   +4 more sources

PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics

BMC Anesthesiology, 2002
Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for this analysis.
Levitt David G
doaj   +1 more source

Cross-approximate entropy of cortical local field potentials quantifies effects of anesthesia - a pilot study in rats

BMC Neuroscience, 2010
Background Anesthetics dose-dependently shift electroencephalographic (EEG) activity towards high-amplitude, slow rhythms, indicative of a synchronization of neuronal activity in thalamocortical networks. Additionally, they uncouple brain areas in higher
Schwarz Cornelius, Antkowiak Bernd, Hentschke Harald, Kreuzer Matthias, Kochs Eberhard F, Schneider Gerhard   +5 more
doaj   +1 more source