Results 131 to 140 of about 338,793 (308)

Theoretical perspectives: sociology and the conservation of scientific heritage

open access: yesFrontiers in Sociology
The following considerations adopt a critical conservation approach to understanding scientific heritage, particularly its intangible aspects. This heritage includes the intellectual and research legacy, encompassing various forms of communication, with ...
Stefano Magnolo, Ana Galán-Pérez
doaj   +1 more source

Cinephilia and Philosophia: Or, Why I Don't Show The Matrix in Philosophy 101 [PDF]

open access: yes, 2017
The shelves of film and philosophy books should have made it considerably easier to teach with films in introductory philosophy classes, and certainly many philosophers have found them useful.
Yenter, Timothy
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Enhancing group outcomes: the role of individual preparation in collaborative learning

open access: yesBMC Medical Education
Background Individual preparation can enhance the effects of collaborative learning through effective information processing. However, the limitations of prior studies in distinguishing the unique effects of individual preparation from individual ...
Min Hae Song   +4 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Post-digital humanities: computation and cultural critique in the arts and humanities [PDF]

open access: yes, 2014
Today we live in computational abundance whereby our everyday lives and the environment that surrounds us are suffused with digital technologies. This is a world of anticipatory technology and contextual computing that uses smart diffused computational ...
Berry, David M
core   +1 more source

Enabling Intentional Human Engagement with AI

open access: yesUbiquity
In this interview, Ubiquity's senior editor, Dr. Bushra Anjum, chats with Ming Yin, an assistant professor at Purdue University, about how intentional human interactions can fully realize the potential of AI in augmenting human intelligence. We also discuss Dr.
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Introduction

open access: yes, 2022
Meissner, Miriam   +2 more
openaire   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

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