Results 41 to 50 of about 1,876,545 (254)
Self-oriented, other-oriented, and socially prescribed perfectionism in employees: Relationships with burnout and engagement [PDF]
, 2010 Burnout and engagement impact employees, organizations, and customers in numerous positive and negative ways. Consequently, it is important to know how individual differences contribute to employees‘ burnout and engagement. The present study examined how
Stoeber, Joachim +3 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Assessing public engagement with science in a university primate research centre in a national zoo [PDF]
, 2012 Recent years have seen increasing encouragement by research institutions and funding bodies for scientists to actively engage with the public, who ultimately finance their work.
Mark T Bowler +12 more
core +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Digitalisierung, Klimaschutz und Engagement
, 2022 Herr Kolain hielt den Vortrag online über zoom bei der BBE-Arbeitsgruppe "Digitalisierung und Bürgerschaftliches Engagement" am 02.02 ...
Kolain, Michael
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Manager-Analyst Engagement and Stock Return Synchronicity [PDF]
Research has shown that the market actively interprets information conveyed in question and answer (Q&A) conversations during conference calls. However, previous studies have not clearly indicated how this information influences the market.
Chen, Minjia +3 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2017 Welcome to the fifth volume of the International Journal of Research on Service-Learning and Community Engagement (IJRSLCE), the annual, online, peer-reviewed publication of the International Association for Research on Service-Learning and Community ...
Richard, Dan, Perry, Lane
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