Results 51 to 60 of about 1,876,545 (254)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Community engagement in rural-remote and Indigenous local government [PDF]
, 2012 This study aims to further explore this priority capacity building issue to provide insight to the community engagement practices and challenges of rural-remote and Indigenous local government in Australia for the purpose of identifying some practical ...
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
ENGAGE-DEM : a model of engagement of people with dementia
, 2023 Dementia is a neurodegenerative disease that affects cognition, producing a reduction in thinking, problem-solving, and mnemonic abilities, functioning, preventing affected people to care for themselves and carry out activities of daily living (e.g., self-feeding, dress oneself), and psychosocial well-being, causing the appearance of disorders of ...
openaire +4 more sources
, 2001 University of Minnesota: Office for Public Engagement. (2001). Civic Engagement Inventory.
University of Minnesota: Office for Public Engagement
core
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
NSSE 2022 Engagement Indicators [PDF]
, 2022 Engagement Indicators (EIs) provide a useful summary of the detailed information contained in your students’ NSSE responses. By combining responses to related NSSE questions, each EI offers valuable information about a distinct aspect of student ...
National Survey of Student Engagement
core +1 more source
Office for Public Engagement: Student Experiences
, 2008 University of Minnesota: Office for Public Engagement. (2008). Office for Public Engagement: Student Experiences.
University of Minnesota: Office for Public Engagement
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Amplify Engagement Report presents findings from the Children with Incarcerated Parents (CHIRP) study, which aims to estimate the number of children affected by parental incarceration across five Canadian provinces (British Columbia, Alberta ...
Engagement, Amplify
core +1 more source