Results 121 to 130 of about 965,816 (315)
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Self-oscillations in an Alpha Stirling Engine: a bifurcation analysis
, 2019 We study a thermo-mechanical system comprised of an alpha Stirling engine and a flywheel from the perspective of dynamical systems theory. Thermodynamics establish a static relation between the flywheel's angle and the forces exerted by the two power ...
Castanos, Fernando, Gromov, Dmitry
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
SensorsThis study presents the development and validation of an in situ monitoring method for the laser direct energy deposition (DED) process, utilizing an integrated optical camera (720 HD, 60 fps) to analyze melt pool imagery.
Rustam Paringer +3 more
doaj +1 more source
Approximate theoretical performance evaluation for a diverging rocket [PDF]
, 1960 A simplified combustion model, which is motivated by available performance studies on the diverging rocket reactor, has been used as basis for an engine performance evaluation.
Eckel, E. F. +3 more
core
Large deviation analysis of a simple information engine
, 2015 Information thermodynamics provides a framework for studying the effect of feedback loops on entropy production. It has enabled the understanding of novel thermodynamic systems such as the information engine which can be seen as a modern version of ...
Grosskinsky, Stefan +2 more
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Detecting faults in electronic combustion engine control systems by acoustic parameters
Вестник СибАДИIntroduction. The process of ensuring the operability of transport and technological machines (TTM) presupposes regular checking of its technical condition by diagnosing various units, assemblies and systems, including electronic systems for monitoring ...
V. D. Gabidulin, V. N. Dobromirov
doaj +1 more source
Energy efficient engine high pressure turbine ceramic shroud support technology report [PDF]
This work represents the development and fabrication of ceramic HPT (high pressure turbine) shrouds for the Energy Efficient Engine (E3). Details are presented covering the work performed on the ceramic shroud development task of the NASA/GE Energy ...
Carlson, R. G., Nelson, W. A.
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source