Results 71 to 80 of about 82,857 (303)

Modeling of multifunctional porous tissue scaffolds with continuous deposition path plan [PDF]

, 2012
A novel modeling technique for porous tissue scaffolds with targeting the functionally gradient variational porosity with continuous material deposition planning has been proposed.
Khoda, AKM B., Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +4 more
core   +1 more source

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

Advanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro, Telmo Lopes, André F. Silva, Carmel Majidi, Mahmoud Tavakoli   +4 more
wiley   +1 more source

Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trialResearch in context

EBioMedicine
Summary: Background: In preclinical studies, the use of double allogeneic grafts has shown promising results in promoting tissue revascularization, reducing infarct size, preventing adverse remodelling and fibrosis, and ultimately enhancing cardiac ...
Antoni Bayes-Genis, Paloma Gastelurrutia, Marta Monguió-Tortajada, Maria Luisa Cámara, Cristina Prat-Vidal, German Cediel, Luciano Rodríguez-Gómez, Albert Teis, Elena Revuelta-López, Gemma Ferrer-Curriu, Santiago Roura, Carolina Gálvez-Montón, Felipe Bisbal, Joaquim Vives, Anna Vilarrodona, Christian Muñoz-Guijosa, Sergi Querol   +16 more
doaj   +1 more source

Electrospun Scaffolds and Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Cardiac Tissue Engineering Applications

Bioengineering, 2020
Tissue engineering (TE) combines cells, scaffolds, and growth factors to assemble functional tissues for repair or replacement of tissues and organs. Cardiac TE is focused on developing cardiac cells, tissues, and structures—most notably the heart.
Taylor Cook Suh, Alaowei Y. Amanah, Jessica M. Gluck   +2 more
doaj   +1 more source

Directed fusion of cardiac spheroids into larger heterocellular microtissues enables investigation of cardiac action potential propagation via cardiac fibroblasts. [PDF]

PLoS ONE, 2018
Multicellular spheroids generated through cellular self-assembly provide cytoarchitectural complexities of native tissue including three-dimensionality, extensive cell-cell contacts, and appropriate cell-extracellular matrix interactions.
Tae Yun Kim, Celinda M Kofron, Michelle E King, Alexander R Markes, Amenawon O Okundaye, Zhilin Qu, Ulrike Mende, Bum-Rak Choi   +7 more
doaj   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Electroconductive biomaterials for cardiac tissue engineering

Acta Biomaterialia, 2022
Myocardial infarction (MI) is still the leading cause of mortality worldwide. The success of cell-based therapies and tissue engineering strategies for treatment of injured myocardium have been notably hindered due to the limitations associated with the selection of a proper cell source, lack of engraftment of engineered tissues and biomaterials with ...
Hamid Esmaeili, Alejandra Patino-Guerrero, Masoud Hasany, Mohammad Omaish Ansari, Adnan Memic, Alireza Dolatshahi-Pirouz, Mehdi Nikkhah   +6 more
openaire   +3 more sources

Engineering cardiac tissue: The role of topographic cues in cardiomyocytes

Journal of Applied Biomaterials & Functional Materials
Cardiovascular diseases represent a leading cause of mortality on a global scale. Engineered cardiac tissue applied as in vitro model have great potential on discovering myocardium pathology mechanisms and developing new drugs.
Maoyu Qin, Xinyi Chen, Ping Zhu
doaj   +1 more source

Tissue-engineered human embryonic stem cell-containing cardiac patches: evaluating recellularization of decellularized matrix

Journal of Tissue Engineering, 2020
Decellularized cardiac extracellular matrix scaffolds with preserved composition and architecture can be used in tissue engineering to reproduce the complex cardiac extracellular matrix.
Camila Hochman-Mendez, Dilza Balteiro Pereira de Campos, Rafael Serafim Pinto, Bernardo Jorge da Silva Mendes, Gustavo Miranda Rocha, Gustavo Monnerat, Gilberto Weissmuller, Luiz C Sampaio, Adriana Bastos Carvalho, Doris A Taylor, Antonio Carlos Campos de Carvalho   +10 more
doaj   +1 more source

Conductive nanomaterials for cardiac tissues engineering

Engineered Regeneration, 2020
Myocardial infarction (MI) is a worldwide disease with high incidence and high fatality rate. In the past decade, a lot of research work based on the method of cardiac tissues engineering has received wide attention from researchers and has been ...
Wei Liu, Luming Zhao, Changyong Wang, Jin Zhou   +3 more
doaj   +1 more source