Results 61 to 70 of about 1,238,092 (290)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

REQUIREMENTS ENGINEERING FOR CLOUD COMPUTING ADAPTIVE MODEL

open access: yesJournal of ICT, 2016
The easy access and flexibility provided by cloud computing have made various types of organizations use this technology as an alternative solution. However, the decision to use the cloud technology sometimes ignores the basic aspects related to the ...
Kridanto Surendro   +2 more
doaj  

A New Role for Human Resource Managers: Social Engineering Defense [PDF]

open access: yes, 2016
[Excerpt] The general risk of social engineering attacks to organizations has increased with the rise of digital computing and communications, while for an attacker the risk has decreased.
Seidenberger, Scott
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Collaborative Engineering of Inter-Enterprise Business Processes [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2011
Enterprise 2.0 and cloud computing are two of the last years most popular topics. Researchers and Business Analysts see great opportunities and potential for a kind of business application revolution.
Gunter Teichmann   +2 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Advanced Brain‐on‐a‐Chip for Wetware Computing: A Review

open access: yesAdvanced Science
In pursuit of low‐power consumption and surpassing computational limitations of silicon‐based chips, people are beginning to seek more efficient computing devices, such as Wetware Computing.
Shangchen Li   +11 more
doaj   +1 more source

A multiple-data-based efficient global optimization algorithm and its parallel implementation for automotive body design

open access: yesAdvances in Mechanical Engineering, 2018
The purpose of this article is to improve the convergence efficiency of the traditional efficient global optimization method. Furthermore, we try a graphics processing unit–based parallel computing method to improve the computing efficiency of the ...
Bing Xu, Yong Cai
doaj   +1 more source

Application Research of the Parallel System Theory and the Data Engine Approach in Wind Energy Conversion System

open access: yesEnergies, 2019
The parallel system is a kind of scientific research method based on an artificial system and computational experiments, which can not only reflect the dynamic process of the real system but also optimize its control process in real time. Given the rapid
Zhicheng Lin   +4 more
doaj   +1 more source

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