Results 61 to 70 of about 261,539 (254)

A regional technology transfer program [PDF]

open access: yes
The final report is presented for the North Carolina Science and Technology Research Center's 14th consecutive contract period as a NASA Industrial Applications Center, serving the information needs of nine Southeastern states. Included in the report are

core   +1 more source

Close Fire Support: Sexton Self-Propelled Guns of the 23rd Field Regiment, 1942–1945 [PDF]

open access: yes, 2012
On the battlefields of the First World War, initially successful attacks all too often ended in failure because artillery weapons could not be moved up quickly enough to support assault infantry at the sharp end of the fight.
Iarocci, Andrew
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Study to establish cost projections for production of Redox chemicals [PDF]

open access: yes
A cost study of four proposed manufacturing processes for redox chemicals for the NASA REDOX Energy Storage System yielded favorable selling prices in the range $0.99 to $1.91/kg of chromic chloride, anhydrous basis, including ferrous chloride.
Greco, C. C.   +3 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The shape of fisheries to come. Some thoughts on fisheries development and education with special reference to aquaculture [PDF]

open access: yes, 1985
A brief discussion is presented on the current situation regarding world fisheries and the future role of aquaculture. The various components involved in fisheries, and affecting all changes in fisheries through time, include the biology of the species ...
Kutty, M.N.
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Impartial Evaluations of the Printing Quality of Paper [PDF]

open access: yes, 1956
Several methods for the evaluation of paper have been investigated for their desirability as means of an impartial evaluation of the printing quality of paper.
Engel, Warren R.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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