Results 51 to 60 of about 10,289,638 (297)
Optimal design of dampers in seismic applications utilizing the MOPSO algorithm
New technological developments in engineering present an opportunity for improved efficiency in structural design through optimization. High-performance computing resources reduce the time needed for computational calculations. Concurrently, optimization
Mahmoud Baei, Vesna Terzic
doaj +1 more source
Learning Energy Consumption and Demand Models through Data Mining for Reverse Engineering [PDF]
: The estimation of energy demand (by power plants) has traditionally relied on historical energy use data for the region(s) that a plant produces for. Regression analysis, artificial neural network and Bayesian theory are the most common approaches for ...
core +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A vulnerability surface modeling method based on dual intensity metrics is proposed to assess the impact of typhoons and heavy rainfall disasters on the distribution pole-tower conductor system. A three-dimensional finite-element model is developed for a
Haijun Yu +5 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Seismic Response of Plan-Asymmetric Structures with Diaphragm Flexibility
The seismic behavior of asymmetric structures with a flexible diaphragm was studied by conducting inelastic dynamic time-history analyses. Asymmetric structures with different configurations of mass, stiffness, and strength centers, in combination with a
Hamed Eivani +3 more
doaj +1 more source
Modelling production ramp-up of engineering products [PDF]
Companies that introduce new products quickly have been shown to be better performers. The effectiveness of the new product introduction process is critical to their performance. Production ramp-up is a necessary phase of new product introduction, and
Roberts, S. +11 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

