Results 61 to 70 of about 10,289,638 (297)
Inverse design of mode-locked fiber laser by particle swarm optimization algorithm
A wide variety of laser applications, that often require radiation with specific characteristics, and relative flexibility of laser configurations offer a prospect of designing systems with the parameters on demand. The inverse laser design problem is to
Alexey Kokhanovskiy +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Engineering characterisation of estuarine silts [PDF]
Guidance is provided for geotechnical engineers designing civil engineering works in silty soils. A detailed characterisation of two estuarine silt sites in Ireland is performed and the soil properties are linked to their geological origin.
Long, Michael (Michael M.)
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A Statistical Approach to Equivalent Linearization with Application to Performance-Based Engineering [PDF]
A new methodology for calculating optimal effective linear parameters for use in predicting the earthquake response of structures is developed. The methodology is applied to several single-degree-of-freedom inelastic structural models subjected to a ...
Guyader, Andrew Charles +1 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
This study addresses the fundamental need for clean water infrastructure in Semangau Village, Sambas District, through comprehensive engineering design of a water treatment installation.
Arif Parabi +7 more
doaj +1 more source
Microbial protease and cellulase are in high demand by different industries due to their minimal cost and availability. This study was aimed to maximize the production of protease and cellulase using two bacteria, Corynebacterium alkanolyticum ATH3 and ...
Goutam Banerjee +2 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Aggregate employment : demand and supply in the U.K. engineering industry [PDF]
The thesis aims to explain the determination of employment at the industry level - in particular, the S.I.C. Orders of the U.K. engineering industry. The traditional demand-orientated approach is examined theoretically and empirically.
Roberts, Colin J.
core

