Results 71 to 80 of about 2,376,720 (336)

ENGINEERING EDUCATION: FORMAT CHANGE

Высшее образование в России, 2016
The necessity for changes in content and technology of engineering personnel training is discussed. The model of "new" engineering education has been developed and tested as a project at Siberian Federal University in order to find changing mechanisms in
Pavel M. Vcherashny, Natalia V. Gafurova, Maksim V. Rumyantsev, Olga A. Osipenko   +3 more
doaj  

The Giant Leap in the Development of Higher Engineering Education in China

ECNU Review of Education
Purpose This study discusses the development of higher engineering education and its future direction following the increased enrollment in higher education institutions in China.
Zhengyang Wu (邬正阳)
doaj   +1 more source

Engineering enterprise through intellectual property education - pedagogic approaches [PDF]

, 2005
Engineering faculties, despite shrinking resources, are delivering to new enterprise agendas that must take account of the fuzzying of disciplinary boundaries.
Childs, B., Maclaughlan, R., Roach, Jim, Soetendorp, Ruth   +3 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Retractable roofs in engineering education

Technical Transactions, 2020
This paper presents a proposal for updating and expanding the teaching of technical university students concerning the subject of roofs. Through the analysis of Polish textbooks and teaching studies, a lack of information on retractable roofs was ...
Pawlak-Jakubowska Anita, Romaniak Krystyna   +1 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Attracting Minorities To Engineering Careers: Addressing The Challenges From K 12 To Postsecondary Education [PDF]

, 2020
Jonathan Lambright, Wayne Johnson, Cameron Coates   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

ENGINEERING EDUCATION: PRACTICE-ORIENTED APPROACH

Высшее образование в России, 2017
The paper substantiates the need to strengthen the practical orientation of engineering education in modern socio-economic conditions. The paper shows that introduction of context-related tasks during classroom hours correspond to the implementation of ...
N. N. Dvulichanskaya, V. B. Piasetsky
doaj