Results 111 to 120 of about 5,632,873 (248)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Responsible use of Generative AI in chemical engineering
Digital Chemical EngineeringGenerative Artificial Intelligence is a rapidly developing area being used to create powerful tools which have the potential to change a wide range of professional practices in chemical engineering.
Thorin Daniel, Jin Xuan
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Ethics of engineering education [PDF]
, 2009 Ethics of Engineering Education is a result of an international conference organized by the Faculty of Engineering, International Islamic University Malaysia.
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Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
A Meta-Synthesis of Ethics-Aware Software Engineering Practice: A Preliminary Framework
Journal of Information Systems and InformaticsThe use of evidence-based practice to inform ethical software development is important for all stakeholders to achieve successful software and address the ethical needs of those affected by it.
Senyeki Milton Marebane, Ernest Mnkandla
doaj +1 more source
The Concept of Integrity and Its Application to Engineering Ethics [PDF]
, 2014 Integrity is a common and well established concept in the ethical vocabulary. It is also being used in various codes of ethics, and investigated by means of various methods.
Wajszczyk, Piotr
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Economics and Ethics: Heritage of Amartya Sen
, 2013 Amartya Sen is currently working on enriching the discipline of economics through the introduction of new propositions. One of these propositions, developed by himself and based on Adam Smith, is an approach to economy in harmony with ethics.
Levent, Adem
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