Results 51 to 60 of about 840,567 (303)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

TEACHING OF ETHICS IN ENGINEERING UNDERGRADUATE PROGRAMS: TECNOLÓGICO NACIONAL DE MÉXICO’S CASE

open access: yesRa Ximhai, 2019
Considering the huge boom that the integration of ethical notions in college education has had in universities around the world, this work is a research about this process in Mexico’s National Tech (TecNM).
Jorge Alberto Olayo-Valles   +3 more
doaj   +1 more source

Investigating the emphasis on the educational ethics at the engineering universities of Iran and comparing it with top engineering universities of the world

open access: yesآموزش مهندسی ایران, 2020
The purpose of this research is to investigate the emphasis on the educational ethics at the engineering universities of Iran and comparing with top engineering universities of the world.
Hossein Abdullahi   +1 more
doaj   +1 more source

Teaching engineering ethics with sustainability as context [PDF]

open access: yes, 2012
Purpose – The purpose of this paper is to ascertain the engagement and response of students to the teaching of engineering ethics incorporating a macro ethical framework whereby sustainability is viewed as context to professional practice.
Byrne, Edmond P.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Engineering Ethics is Global Concerning

open access: yesآموزش مهندسی ایران, 2010
Engineering ethics and morals in engineering are rather new subjects in engineering education and activities. Because of engineering activities which create and change the world, as well as to sustain the world life, deals with a new definition of ...
Jalal Hejazi
doaj   +1 more source

The Concept of Integrity and Its Application to Engineering Ethics [PDF]

open access: yes, 2014
Integrity is a common and well established concept in the ethical vocabulary. It is also being used in various codes of ethics, and investigated by means of various methods.
Wajszczyk, Piotr
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Identifying and Ranking the Components of Engineering Ethics with a Multi-Criteria Decision-Making Approach

open access: yesآموزش مهندسی ایران, 2020
Engineering ethics deals with moral issues and decisions confronting individuals and organizations engaged in engineering, and it is, therefore, the ability and the responsibility of all engineers to evaluate their decisions based on the general well ...
mahdi safaei   +3 more
doaj   +1 more source

Values in Water [PDF]

open access: yes, 2018
Inaugural speech spoken in acceptance of the chair ‘Ethics of water engineering’ at the Faculty of Technology, Policy and Management of Delft University of Technology on 16 November ...
Doorn, Neelke
core  

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