Results 61 to 70 of about 5,632,873 (248)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Teaching Engineering Ethics Through a Psychology Course [PDF]

open access: yes, 2021
While ethics instruction is now widespread, studies are still looking for different ways to integrate ethics in engineering programs. In this article, we propose a novel approach by teaching engineering ethics through a psychology course.
Canh, Phan Thi Thanh   +5 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Failure of Engineering Artifacts: A Life Cycle Approach [PDF]

open access: yes, 2012
Failure is a central notion both in ethics of engineering and in engineering practice. Engineers devote considerable resources to assure their products will not fail and considerable progress has been made in the development of tools and methods for ...
Luca Del Frate, Del Frate, L. (author)
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

ENGINEERING ETHICS AT TECHNICAL UNIVERSITY

open access: yesВысшее образование в России, 2016
The article covers the issues concerning the formation of engineers' social and cultural competences at higher education institutions. The concept of science and engineering moral neutrality is receding into the past, engineering education standards ...
Alfred A. Dulzon, Ekaterina V. Galanina
doaj  

Rethinking sustainability in engineering education: a call for systemic change

open access: yesFrontiers in Education
The integration of engineering education with sustainability is a major requirement in overcoming global environmental, social, and economic challenges.
Omar K. Sabri
doaj   +1 more source

The Design Education of the New Era Urgent Needs to Cultivate Engineering Ethics Consciousness

open access: yesMATEC Web of Conferences, 2018
By expounding the inseparable relationship between design and engineering ethics, and comparing the current situation of the development of engineering ethics education at home and abroad, we find that there is a big gap between China's design ...
Wenming Liu
doaj   +1 more source

Soft skills for engineering students and graduates

open access: yesآموزش مهندسی ایران, 2019
The purpose of this study was to investigate the compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University and its related factors.
Ali Mohammadzadeh   +1 more
doaj   +1 more source

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