Results 61 to 70 of about 322,991 (265)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The Design Education of the New Era Urgent Needs to Cultivate Engineering Ethics Consciousness
MATEC Web of Conferences, 2018 By expounding the inseparable relationship between design and engineering ethics, and comparing the current situation of the development of engineering ethics education at home and abroad, we find that there is a big gap between China's design ...
Wenming Liu
doaj +1 more source
Soft skills for engineering students and graduates
آموزش مهندسی ایران, 2019 The purpose of this study was to investigate the compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University and its related factors.
Ali Mohammadzadeh +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
ENGINEERING ETHICS AT TECHNICAL UNIVERSITY
Высшее образование в России, 2016 The article covers the issues concerning the formation of engineers' social and cultural competences at higher education institutions. The concept of science and engineering moral neutrality is receding into the past, engineering education standards ...
Alfred A. Dulzon, Ekaterina V. Galanina
doaj
آموزش مهندسی ایران, 2019 The purpose of this study was to investigate the compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University and its related factors.
ali imanzadeh +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source