Results 71 to 80 of about 840,567 (303)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University

آموزش مهندسی ایران, 2019
The purpose of this study was to investigate the compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University and its related factors.
ali imanzadeh , Aysan Pashaiefakhri, haniye kalantari   +2 more
doaj   +1 more source

Employer and student perspectives on skills for engineers in the twenty first century and beyond [PDF]

, 2010
This research focused on skills identified among final year engineering students. It provided evidence of different levels of skills by students and identifies their greatest learning influences in these areas.
Brabazon, Dermot, McMorrow, Denise, Naher, Sumsun   +2 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Design Education of the New Era Urgent Needs to Cultivate Engineering Ethics Consciousness

MATEC Web of Conferences, 2018
By expounding the inseparable relationship between design and engineering ethics, and comparing the current situation of the development of engineering ethics education at home and abroad, we find that there is a big gap between China's design ...
Wenming Liu
doaj   +1 more source

Soft skills for engineering students and graduates

آموزش مهندسی ایران, 2019
The purpose of this study was to investigate the compliance of electrical engineering ethics codes among students of electrical faculty of Tabriz University and its related factors.
Ali Mohammadzadeh, Rahmat Sotudeh gharebagh   +1 more
doaj   +1 more source

Teaching Engineering Ethics With The Engineering Ethics Challenge Game [PDF]

2005 Annual Conference Proceedings, 2020
Comment: 13 ...
openaire   +2 more sources

We Could, but Should We? Ethical Considerations for Providing Access to GeoCities and Other Historical Digital Collections [PDF]

, 2020
We live in an era in which the ways that we can make sense of our past are evolving as more artifacts from that past become digital. At the same time, the responsibilities of traditional gatekeepers who have negotiated the ethics of historical data ...
Bastian M., Cohen D., Dent P., Frankel C., Hallinan B., Jenkins H., Klein E., Lin J., McTavish S., Milligan I., Milligan I., Smith M.   +11 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source