Results 81 to 90 of about 840,567 (303)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Software engineering ethics [PDF]

Software engineering ethics is reviewed. The following subject areas are covered: lack of a system viewpoint; arrogance of PC DOS software vendors; violation od upward compatibility; internet worm; internet worm revisited; student cheating and company ...
Bown, Rodney L.
core   +1 more source

Forming engineers' sociocultural competence: Engineering ethics at Tomsk polytechnic university [PDF]

, 2015
The aim of the present research is to discuss Tomsk Polytechnic University in respect of forming engineers' sociocultural competence and teaching engineering ethics. Today international standards of training engineers cover efficient communication skills,
Dulson, Alfred Andreewitsch, Galanina, Ekaterina Vladimirovna, Schwab, A.   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

ENGINEERING ETHICS AT TECHNICAL UNIVERSITY

Высшее образование в России, 2016
The article covers the issues concerning the formation of engineers' social and cultural competences at higher education institutions. The concept of science and engineering moral neutrality is receding into the past, engineering education standards ...
Alfred A. Dulzon, Ekaterina V. Galanina
doaj  

Rethinking sustainability in engineering education: a call for systemic change

Frontiers in Education
The integration of engineering education with sustainability is a major requirement in overcoming global environmental, social, and economic challenges.
Omar K. Sabri
doaj   +1 more source

An Introduction to the Integrated Community-Engaged Learning and Ethical Reflection Framework (I-CELER) [PDF]

, 2018
Cultivating ethical Science, Technology, Engineering, and Mathematics researchers and practitioners requires movement beyond reducing ethical instruction to the rational exploration of moral quandaries via case studies and into the complexity of the ...
Coleman, Martin A., Fore, Grant A., Hahn, Thomas William, Hatcher, Julie Adele, Hess, Justin L., Price, Mary F., Sorge, Brandon   +6 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Ethics in engineering: Student perceptions and their professional identity development

Journal of Technology and Science Education, 2013
Professional ethics instruction in engineering is commonly conducted by examining case studies in light of the code of conduct of a suitable professional body.
Brad Stappenbelt
doaj   +1 more source

Teaching Ethics for Construction Management Majored Students: Standalone or Micro-insert? – Globalization and Sustainability Considerations [PDF]

, 2016
This paper is part of the conference proceedings of the American Society for Engineering Education 's 123rd Annual Conference and Exposition in New Orleans, LA in June 2016.
Buckeridge, John S., Wang, George
core   +1 more source