Results 81 to 90 of about 330,550 (310)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
An Ancient Dilemma: A case study for use in teaching in Engineering Ethics
, 2010 This is an Engineering Ethics case study from the IDEA CETL. The scenario examines the case of a conflict between completing a project on time and within budget and respecting the demands of heritage.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
BuildingsWith the rapid development of engineering construction in China, especially the emergence of large-scale engineering projects and self-built residential houses, ethical issues in engineering have become increasingly prominent.
Dina Tang, Minshui Huang
doaj +1 more source
CV Joints: A case study for use in teaching in Engineering Ethics
, 2010 This is an Engineering Ethics case study from the IDEA CETL. The scenario examines issues around the intellectual property of an idea possibly inspired by working at a company.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds +2 more
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The Engineer as an Educator: Goods, Virtues, and Secondary Practices
Studies in Logic, Grammar and RhetoricHow should ethical standards be maintained within engineering and engineering education? The present paper addresses this question with relation to the dominant models of engineering ethics (EE) to show that their limits might be overcome by ...
Machura Piotr
doaj +1 more source
Ethics in engineering: Student perceptions and their professional identity development
Journal of Technology and Science Education, 2013 Professional ethics instruction in engineering is commonly conducted by examining case studies in light of the code of conduct of a suitable professional body.
Brad Stappenbelt
doaj +1 more source
Transmission Towers: A case study for use in teaching in Engineering Ethics
, 2010 This is an Engineering Ethics case study from the IDEA CETL. It examines the moral issues surrounding a disagreement with a boss at work concerning the safety of a transmission tower. It considers safety and risk and whistleblowing.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds +1 more
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source