Results 81 to 90 of about 5,632,873 (248)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Ethics in engineering: Student perceptions and their professional identity development
Journal of Technology and Science Education, 2013 Professional ethics instruction in engineering is commonly conducted by examining case studies in light of the code of conduct of a suitable professional body.
Brad Stappenbelt
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
TOWARD SOFTWARE ENGINEERING PRINCIPLES BASED ON ISLAMIC ETHICAL VALUES
International Islamic University Malaysia Engineering Journal, 2010 Software is the core for Computer-based applications which became an essential part for critical control systems, health and human life guard systems, financial and banking systems, educational and other systems.
shihab A. Hameed
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
A foretaste of engineering ethics
, 2002 Following a spate of major engineering disasters in the recent past, the prominence of technology underlying our civilisation became more apparent to the public at large.
Ilic, Vojislav
core
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
CONFUCIAN ENVIRONMENTAL ETHICS, CLIMATE ENGINEERING, AND THE “PLAYING GOD” ARGUMENT
Zygon, 2015 The burgeoning literature on the ethical issues raised by climate engineering has explored various normative questions associated with the research and deployment of climate engineering, and has examined a number of responses to them.
doaj +2 more sources
Ethics in an engineering curriculum
, 2003 Although Ethics and Engineering have existed as separate academic entities for a long time, it is only comparatively recently that the former formally became a part of the engineering profession and an accepted component of an engineering curriculum ...
Ilic, Vojislav
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source