Results 101 to 110 of about 1,321,882 (316)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Journal of Industrial Design and Engineering Graphics, 2010 The paper presents general notions about graphical language used in engineering, the international standards used for representing objects and also the most important software applications used in Computer Aided Design for the development of products in ...
BADEA Florina, PETRESCU Ligia
doaj
GEO: Generative Engine Optimization
Proceedings of the 30th ACM SIGKDD Conference on Knowledge Discovery and Data MiningThe advent of large language models (LLMs) has ushered in a new paradigm of search engines that use generative models to gather and summarize information to answer user queries. This emerging technology, which we formalize under the unified framework of generative engines (GEs), can generate accurate and personalized responses, rapidly replacing ...
Pranjal Aggarwal +5 more
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Soliton generation and control in engineered materials
, 2023 Optical solitons provide unique opportunities for the control of light‐bylight. Today, the field of soliton formation in natural materials is mature, as the main properties of the possible soliton states are well understood. In particular, optical solitons have been observed experimentally in a variety of materials and physical settings, including ...
openaire +4 more sources
IN THE MATTER OF AN APPLICATION TO THE COMPTROLLER-GENERAL BY THE LOEWY ENGINEERING COY. LD. UNDER SEC. 56 OF THE ACT [PDF]
, 1952 openalex +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Generative vs. Non-Generative Models in Engineering Shape Optimization
Journal of Marine Science and EngineeringGenerative models offer design diversity but tend to be computationally expensive, while non-generative models are computationally cost-effective but produce less diverse and often invalid designs. However, the limitations of non-generative models can be overcome with the introduction of augmented shape signature vectors (SSVs) to represent both ...
Zahid Masood +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
General and engineering geology of the northern part of Pueblo, Colorado [PDF]
, 1969 G. Richard Scott
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