Results 101 to 110 of about 9,706,975 (343)

Comments on the problems solving methodology in education of civil engineering in Brazil

Revista Brasileira de Ensino de Ciência e Tecnologia, 2019
Academic works have indicated which didactic methods to teaching engineers fail in the professional preparation, despite the international effort to create competences for engineering students.
Paloma Aparecida Alves, Tales Alexandre Aversi-Ferreira   +1 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Improving the thermal properties of lightweight concrete exterior walls [PDF]

E3S Web of Conferences
This article is devoted to the development of energy-efficient porous expanded clay concrete for exterior walls. Experimental data confirming the expediency of designing the optimal composition of porous concrete according to the general method of ...
Goncharova Natalia, Ababakirova Zebuniso, Davlyatov Shokhrukh, Umarov Shodiljon, Mirzababayeva Sahiba   +4 more
doaj   +1 more source

Describing 'generic' graduate engineer skills

, 2018
Project-Based Learning, Qualitative Research, Grounded Theory, Creativity Being able to describe skills effectively is essential for teaching and enabling students to learn skills. A previous study [1], investigating the development of real industrial problem solving skills in a taught Masters course, found inadequate skill descriptions were a ...
Shawcross, JK, Ridgman, Tom W
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Local microenvironment reactive zone engineering promotes water activation

Materials Reports: Energy
Beyond conventional electrocatalyst engineering, recent studies have demonstrated the effectiveness of manipulating the local reaction environment to enhance the performance of electrocatalytic reactions.
Jian Luo, Junjie Zheng, Mingjie Wu, Fang Dong, Yuyu Liu, Jinli Qiao, Yingkui Yang   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source