Results 81 to 90 of about 5,076,354 (301)

Energy efficiency in civil engineering: analyzing world experience

MATEC Web of Conferences, 2018
There are consistent trends in the development of energy-saving technologies in civil engineering in almost all countries of the world. The article considers the main approaches to ensuring energy efficiency in in civil engineering, analyzes the ...
Bezdenezhnukh Tatiana, Kuritsyn Andrey, Gimelshtein Irina   +2 more
doaj   +1 more source

GEO: Generative Engine Optimization

Proceedings of the 30th ACM SIGKDD Conference on Knowledge Discovery and Data Mining
The advent of large language models (LLMs) has ushered in a new paradigm of search engines that use generative models to gather and summarize information to answer user queries. This emerging technology, which we formalize under the unified framework of generative engines (GEs), can generate accurate and personalized responses, rapidly replacing ...
Pranjal Aggarwal, Vishvak Murahari, Tanmay Rajpurohit, Ashwin Kalyan, Karthik Narasimhan, Ameet Deshpande   +5 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Ethics – research, engineering, design… they’re all the same aren’t they? [PDF]

, 2014
This paper considers how and to what extent product design ethics is understood by professionals in design practice and undergraduate students of product and engineering design and how, if at all, design ethics differ from engineering and/or research ...
Blount, G., Humphries-Smith, Tania, Powell, J.   +2 more
core  

Safe Neighborhood Computation for Hybrid System Verification

, 2015
For the design and implementation of engineering systems, performing model-based analysis can disclose potential safety issues at an early stage. The analysis of hybrid system models is in general difficult due to the intrinsic complexity of hybrid ...
Deng, Yi, Julius, Agung
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A Comparison of Beginning and Advanced Engineering Students’ Description of Information Skills

Evidence Based Library and Information Practice, 2015
Objective – The purpose of this research was to examine how beginning and advanced level engineering students report use of information when completing an engineering design process.
Kerrie Anna Douglas, Amy S. Van Epps, Brittany Mihalec-Adkins, Michael Fosmire, Şenay Purzer   +4 more
doaj   +1 more source

Functional planning and occupational safety of milk production in cold loose housing barns [PDF]

, 2004
The study charted the most serious occupational hazards of cold loose housing barns. Furthermore, the study gave a good general picture of cold loose housing barns (CLHB) in dairy production.
Karttunen, Janne
core  

General chemistry for engineers [PDF]

Journal of Chemical Education, 1982
A logical way introduce polymers into the general chemistry course. From "The Goals of General Chemistry - A Symposium."
openaire   +1 more source