Results 71 to 80 of about 5,076,354 (301)

Gouy-Stodola Theorem as a variational principle for open systems [PDF]

open access: yes, 2012
The recent researches in non equilibrium and far from equilibrium systems have been proved to be useful for their applications in different disciplines and many subjects.
Lucia, Umberto
core   +4 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Teaching ethics to engineering undergraduates - lessons learned and a guide for lecturers: perspective from an English University [PDF]

open access: yes, 2012
The issue of ethics within engineering profession has been gaining more and more importance due to globalisation, increasing awareness of sustainability and the fast changing business culture within engineering organisations.
Hasan, Reaz
core  

Generic Comparison of Protein Inference Engines

open access: yesMolecular & Cellular Proteomics, 2012
Protein identifications, instead of peptide-spectrum matches, constitute the biologically relevant result of shotgun proteomics studies. How to appropriately infer and report protein identifications has triggered a still ongoing debate. This debate has so far suffered from the lack of appropriate performance measures that allow us to objectively assess
Claassen M.   +4 more
openaire   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Evaluation of compatibility and differences of liquefaction prediction methods based on different in-situ tests

open access: yesYantu gongcheng xuebao
Three liquefaction prediction methods, namely in-situ standard penetration test (SPT), shear wave velocity test (Vs), and cone penetration test (CPT), are gradually being incorporated into the codes.
YUAN Jinyuan , LI Weijia , WANG Tao , WANG Yingying
doaj   +1 more source

What Engineering Sophomores Know and Would Like to Know About Engineering Information Sources and Access.

open access: yesIssues in Science and Technology Librarianship, 2009
This exploratory study reports on what engineering undergraduate students know and would like to learn about engineering information sources and access.
Zorana Ercegovac
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Analysis of the scientific production of the Spanish Software Engineering Community [PDF]

open access: yes, 2015
Our group has been working on a report for the Spanish Society of Software Engineering and Software Development Technologies (SISTEDES) to provide a general overview of the Spanish scientific production and its contributions worldwide in the field of ...
Burgueño, Loli   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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