Results 51 to 60 of about 5,028,054 (300)

Stress detection through prompt engineering with a general-purpose LLM

Acta Psychologica
Advancements in large language models (LLMs) have opened new avenues for mental health monitoring through social media analysis. In this study, we present an iterative prompt engineering framework that significantly enhances the performance of the ...
Nima Esmi, Asadollah Shahbahrami, Yasaman Nabati, Bita Rezaei, Georgi Gaydadjiev, Peter de Jonge   +5 more
doaj   +1 more source

Gouy-Stodola Theorem as a variational principle for open systems [PDF]

, 2012
The recent researches in non equilibrium and far from equilibrium systems have been proved to be useful for their applications in different disciplines and many subjects.
Lucia, Umberto
core   +4 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Engineering Students' Citation Skills: Instructor Perspectives and Educational Implications

Issues in Science and Technology Librarianship
This article addresses the oft-noted gap between the amount of instruction students have received and the citation knowledge they demonstrate once they reach discipline-specific courses.
Kristy Kelly, Diana Park, Adam Lindsley, Laurie Bridges   +3 more
doaj   +1 more source

ECNet is an evolutionary context-integrated deep learning framework for protein engineering

Nature Communications, 2021
Protein engineering is an active area of research in which machine learning has proven quite powerful. Here, the authors present a deep learning method that integrates both general and protein-specific sequence representations to improve the engineering ...
Yunan Luo, Guangde Jiang, Tianhao Yu, Yang Liu, Lam Vo, Hantian Ding, Yufeng Su, Wesley Wei Qian, Huimin Zhao, Jian Peng   +9 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Targeting engineering synchronization in chaotic systems

, 2015
A method of targeting engineering synchronization states in two identical and mismatch chaotic systems is explained in details. The method is proposed using linear feedback controller coupling for engineering synchronization such as mixed synchronization,
Bhowmick, Sourav K., Ghosh, Dibakar
core   +1 more source

Advances in the Design and Implementation of a Multi-Tier Architecture in the GIPSY Environment [PDF]

, 2009
We present advances in the software engineering design and implementation of the multi-tier run-time system for the General Intensional Programming System (GIPSY) by further unifying the distributed technologies used to implement the Demand Migration ...
Han, Bin, Mokhov, Serguei A., Paquet, Joey   +2 more
core   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source