Results 41 to 50 of about 1,465,434 (267)

Introducing a general-purpose augmented reality platform for the use in engineering education

open access: yesAdvances in Industrial and Manufacturing Engineering, 2023
There is a lack of a universal Augmented Reality platform which can be used in manufacturing engineering and other education fields to display models, processes, animations and simulations alike.
Joshua Grodotzki   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Engineering Students' Citation Skills: Instructor Perspectives and Educational Implications

open access: yesIssues in Science and Technology Librarianship
This article addresses the oft-noted gap between the amount of instruction students have received and the citation knowledge they demonstrate once they reach discipline-specific courses.
Kristy Kelly   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Graph Generalization for Software Engineering

open access: yesSoftware
Graph generalization is a powerful concept with a wide range of potential applications, while established algorithms exist for generalizing simple graphs, practical approaches for more complex graphs remain elusive. We introduce a novel formal model and algorithm (GGA) that generalizes labeled directed graphs without assuming label identity.
Mohammad Reza Kianifar, Robert J. Walker
openaire   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Calculate large-scale indicators via variation of small-scale data (CLIVS): A general known-to-unknown approach and its application

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
Engineering problems often involve large spatial scales and long-term lifespans. This makes it exceptionally difficult to measure engineering parameters and predict disasters such as slope instability or tunnel collapses.
Shigui Du
doaj   +1 more source

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