Results 41 to 50 of about 5,028,054 (300)

The GOODSTEP project: General Object-Oriented Database for Software Engineering Processes [PDF]

open access: yes, 1994
The goal of the GOODSTEP project is to enhance and improve the functionality of a fully object-oriented database management system to yield a platform suited for applications such as software development environments (SDEs).
Abiteboul, S   +26 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A lightweight, pattern-based approach to identification and formalisation of TimeML expressions in clinical narratives [PDF]

open access: yes, 2012
General Architecture for Text Engineering (GATE) components for identifying clinical events and temporal expressions are developed and evaluated against a corpus of 120 discharge ...
Gooch, P.
core  

Cross-Kerr-based information transfer processes

open access: yes, 2005
The realization of nonclassical states is an important task for many applications of quantum information processing. Usually, properly tailored interactions, different from goal to goal, are considered in order to accomplish specific tasks within the ...
Bose, S.   +5 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Decision Model Research on Engineering Project Arrangement of Power Grid Enterprise Group Based on Input and Output Efficiency Evaluation

open access: yesMATEC Web of Conferences, 2015
The engineering project arrangement of a large-scale Power Grid Enterprise Group confronts optimization problems on how to achieve efficient investment, how to achieve overall balance.
Lu Gang, Luan Hao, He Wan, Ma Yungao
doaj   +1 more source

Ecosystem Engineers in the World Coasts: Case Studies and Conceptual Linkages

open access: yesDiversity, 2020
Research on physical ecosystem engineering—i.e., the structural modification of environments by organisms—has flourished during the last two decades. At present, the importance of physical ecosystem engineers for the biodiversity and the functioning of ...
Jorge L. Gutiérrez
doaj   +1 more source

Introducing a general-purpose augmented reality platform for the use in engineering education

open access: yesAdvances in Industrial and Manufacturing Engineering, 2023
There is a lack of a universal Augmented Reality platform which can be used in manufacturing engineering and other education fields to display models, processes, animations and simulations alike.
Joshua Grodotzki   +2 more
doaj   +1 more source

Generation of genetically-engineered animals using engineered endonucleases [PDF]

open access: yesArchives of Pharmacal Research, 2018
The key to successful drug discovery and development is to find the most suitable animal model of human diseases for the preclinical studies. The recent emergence of engineered endonucleases is allowing for efficient and precise genome editing, which can be used to develop potentially useful animal models for human diseases.
Jong Geol Lee   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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