Results 121 to 130 of about 12,807,066 (354)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Introducing a general-purpose augmented reality platform for the use in engineering education

open access: yesAdvances in Industrial and Manufacturing Engineering, 2023
There is a lack of a universal Augmented Reality platform which can be used in manufacturing engineering and other education fields to display models, processes, animations and simulations alike.
Joshua Grodotzki   +2 more
doaj  

Comments on the problems solving methodology in education of civil engineering in Brazil

open access: yesRevista Brasileira de Ensino de Ciência e Tecnologia, 2019
Academic works have indicated which didactic methods to teaching engineers fail in the professional preparation, despite the international effort to create competences for engineering students.
Paloma Aparecida Alves   +1 more
doaj   +1 more source

Proceedings of the Eighth Annual Software Engineering Workshop [PDF]

open access: yes
The four major topics of discussion included: the NASA Software Engineering Laboratory, software testing, human factors in software engineering and software quality assessment.

core   +1 more source

Reuse through rapid development [PDF]

open access: yes, 2007
The general issue of reuse of digital resources, called Learning Objects (LOs), in education is discussed here. Ideas are drawn from software engineering which has long grappled with the reuse problem.
Costello, Eamon
core  

Comments on Flipped SU(5) (and F-theory)

open access: yes, 2010
We study the impact of nonrenormalizable operators in flipped SU(5) that can generate a large mu term, R-parity violation, and rapid proton decay. While our motivation is to determine whether F-theory can naturally realize flipped SU(5), this analysis is
Kuflik, Eric, Marsano, Joseph
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Engineering Pedagogy in Vocational Education: Methodological Aspect

open access: yesВысшее образование в России, 2018
The paper examines the questions concerning the methodological status of engineering pedagogy in the system of vocational education, specifies its subject area.
P. F. Kubrushko, D. O. Eprikyan
doaj  

Research Laboratory of Electronics Quarterly progress report, period ending 28 Feb. 1967 [PDF]

open access: yes
General physics, plasma dynamics, engineering, and communication sciences programs at Research Laboratory of ...

core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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