Results 41 to 50 of about 9,706,975 (343)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Introducing a general-purpose augmented reality platform for the use in engineering education
There is a lack of a universal Augmented Reality platform which can be used in manufacturing engineering and other education fields to display models, processes, animations and simulations alike.
Joshua Grodotzki +2 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
General, Efficient, and Robust Hamiltonian Engineering
Implementing the time evolution under a desired target Hamiltonian is critical for various applications in quantum science. Due to the exponential increase of parameters in the system size and due to experimental imperfections, this task can be ...
P. Baßler, M. Heinrich, M. Kliesch
doaj +1 more source
General relativity in electrical engineering [PDF]
In electrical engineering metamaterials have been developed that offer unprecedented control over electromagnetic fields. Here we show that general relativity lends the theoretical tools for designing devices made of such versatile materials. Given a desired device function, the theory describes the electromagnetic properties that turn this function ...
Leonhardt, Ulf, Philbin, Thomas G.
openaire +4 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The engineering project arrangement of a large-scale Power Grid Enterprise Group confronts optimization problems on how to achieve efficient investment, how to achieve overall balance.
Lu Gang, Luan Hao, He Wan, Ma Yungao
doaj +1 more source
Ecosystem Engineers in the World Coasts: Case Studies and Conceptual Linkages
Research on physical ecosystem engineering—i.e., the structural modification of environments by organisms—has flourished during the last two decades. At present, the importance of physical ecosystem engineers for the biodiversity and the functioning of ...
Jorge L. Gutiérrez
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
ECNet is an evolutionary context-integrated deep learning framework for protein engineering
Protein engineering is an active area of research in which machine learning has proven quite powerful. Here, the authors present a deep learning method that integrates both general and protein-specific sequence representations to improve the engineering ...
Yunan Luo +9 more
doaj +1 more source

