Results 81 to 90 of about 10,429,289 (298)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Generic Comparison of Protein Inference Engines
Molecular & Cellular Proteomics, 2012 Protein identifications, instead of peptide-spectrum matches, constitute the biologically relevant result of shotgun proteomics studies. How to appropriately infer and report protein identifications has triggered a still ongoing debate. This debate has so far suffered from the lack of appropriate performance measures that allow us to objectively assess
Claassen M. +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Educational Technology & Society, 2021 This article describes STEM education with artificial intelligence (AI) learning, particularly for non-engineering undergraduate students. In the designed three-week learning activities, students were encouraged to put their ideas about AI into practice ...
Chun-Hung Lin +3 more
doaj
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
IL-34 and Immune Checkpoint Inhibitors Resistant through Macrophages: Pan-Cancer Overview
Journal of Inflammation Research, 2023 Mohammed Safi,1,* Al-shaebi Fadhl,1,* Yousif A Algabri,2 Caiqing Zhang1 1Department of Respiratory Diseases, Shandong Second Provincial General Hospital, Shandong University, Jinan, Shandong, People’s Republic of China; 2Department of Biomedical ...
Safi M, Fadhl AS, Algabri YA, Zhang C
doaj
Novìtnâ Osvìta, 2014 The article covers problems related to selecting lexical material for teaching engineers-to-be and surveys the history of the problem. It contains the definition of the "lexical minimum" as a term, and analyses principles of selecting the lexical ...
O. L. Yaroshenko
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Hackathons as experiential learning platforms for engineering design skills
Cogent EducationDuring hackathons, students energetically collaborate in teams, leveraging cutting-edge technologies to tackle real-world challenges in a tight timeframe.
Ricardo Sotaquirá-Gutiérrez +2 more
doaj +1 more source
Journal of Technology and Science Education, 2016 Building a solid foundation of conceptual knowledge is critical for students in electrical engineering. This case study explores the use of simulation videos to illustrate complicated conceptual knowledge in foundational communications and signal ...
Baiyun Chen, Lei Wei, Huihui Li
doaj +1 more source