Results 41 to 50 of about 1,661,640 (282)

Cooperative item collecting problems in directed bipartite structures

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2017
In this paper, a variant of 0-1 knapsack problems in graph structures is considered. Given a directed bipartite structure with a set of items and a set of players, the problem asks to find an arc reversing strategy of the players which collects items ...
Yoshiyuki KARUNO, Seiya TANAKA
doaj   +1 more source

Analysis-of-marginal-Tail-Means (ATM): a robust method for discrete black-box optimization

, 2018
We present a new method, called Analysis-of-marginal-Tail-Means (ATM), for effective robust optimization of discrete black-box problems. ATM has important applications to many real-world engineering problems (e.g., manufacturing optimization, product ...
Mak, Simon, Wu, C. F. Jeff
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Optimization of Lens Adjustment in Semiconductor Lithography Equipment Using Quadratically Constrained and Second-Order Cone Programming

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
The present paper considers optimization of lens adjustment in semiconductor lithography equipment. For improving productivity, the laser irradiation power of recent semiconductor lithography equipment has been boosted, which causes significant ...
Yuji SHINANO, Toshiyuki YOSHIHARA, Ryuhei MIYASHIRO, Youzou FUKAGAWA   +3 more
doaj   +1 more source

An Archive-Based Multi-Objective Arithmetic Optimization Algorithm for Solving Industrial Engineering Problems

IEEE Access, 2022
This research proposes an Archive-based Multi-Objective Arithmetic Optimization Algorithm (MAOA) as an alternative to the recently established Arithmetic Optimization Algorithm (AOA) for multi-objective problems (MAOA).
Nima Khodadadi, Laith Abualigah, El-Sayed M. El-Kenawy, Vaclav Snasel, Seyedali Mirjalili   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Optimization of Segmented Blank Holder Shape and Its Variable Blank Holder Gap in Deep-Drawing Process

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
Optimum segmented blank holder shape and its variable blank holder gaps (VBHGs) are determined by a sequential approximate optimization (SAO) with radial basis function network. In deep drawing, wrinkling and tearing of blank sheet are major defects. The
Jirasak SRIRAT, Koetsu YAMAZAKI, Satoshi KITAYAMA   +2 more
doaj   +1 more source

Strategies for multiobjective genetic algorithm development: Application to optimal batch plant design in process systems engineering [PDF]

, 2008
This work deals with multiobjective optimization problems using Genetic Algorithms (GA). A MultiObjective GA (MOGA) is proposed to solve multiobjective problems combining both continuous and discrete variables.
Azzaro-Pantel, Catherine, Dietz, Adrian, Domenech, Serge, Pibouleau, Luc   +3 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Kinematic Synthesis for Linkages with Velocity Targets

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
A gradient-based optimization method for designing linkages with velocity targets is described. Two theoretical application cases are established for four-bar linkage. In the first, a constant-velocity module is proposed for a point on the coupler.
Ana DE-JUAN, Ramon SANCIBRIAN, Pablo GARCÍA, Fernando VIADERO, Miguel IGLESIAS, Alfonso FERNÁNDEZ   +5 more
doaj   +1 more source