Results 51 to 60 of about 160,456 (265)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Fast EM-driven nature-inspired optimization of antenna input characteristics using response features and variable-resolution simulation models

Scientific Reports
Utilization of optimization technique is a must in the design of contemporary antenna systems. Often, global search methods are necessary, which are associated with high computational costs when conducted at the level of full-wave electromagnetic (EM ...
Slawomir Koziel, Anna Pietrenko-Dabrowska   +1 more
doaj   +1 more source

Simultaneous Optimization of Variable Blank Holder Force Trajectory and Tools Motion in Deep Drawing via Sequential Approximate Optimization

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
In this paper, variable blank holder force (VBHF) trajectory and tools motion are optimized simultaneous by a sequential approximate optimization (SAO) with radial basis function (RBF) network.
Jirasak SRIRAT, Satoshi KITAYAMA, Koetsu YAMAZAKI   +2 more
doaj   +1 more source

Multi-objective optimization of engineering systems using game theory and particle swarm optimization

, 2009
This study proposes particle swarm optimization (PSO) based algorithms to solve multi-objective engineering optimization problems involving continuous, discrete and/or mixed design variables.
Annamdas, Kiran K, Rao, Singiresu S
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Compact design of a redundant manipulator system and application to multiple-goal tasks with temporal constraint

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2017
This paper aims to design a compact manipulator system consisting of a 6 degree-of-freedom (dof) manipulator and a 1-dof rotary table. It proposes a new compactness measure that considers manipulator swept volume or the space occupied by the system while
Lounell Bahoy GUETA, Ryosuke CHIBA, Tamio ARAI, Tsuyoshi UEYAMA, Jose Ildefonso Udang RUBRICO, Jun OTA   +5 more
doaj   +1 more source

Evaluation of sequential, multi-objective, and parallel interactive genetic algorithms for multi-objective optimization problems. [PDF]

, 2006
We propose a sequential interactive genetic algorithm (IGA), multi-objective IGA and parallel IGA, and evaluate them with both simulated and real users.
Ramsden, Jeremy, Tiwari, Ashutosh, Brintrup, A, Tiwari, A, 髙木, 英行, Takagi, Hideyuki, Ramsden, J, ,, Brintrup, Alexandra Melike, Ramsden, Jeremy J., Brintrup, Alexandra   +10 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Heuristic algorithms for a delivery workload balancing problem in an assembly plant

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
In this paper, a delivery workload balancing problem in an assembly plant is considered. The problem is first described as a special case of the unrelated parallel machine scheduling problem of minimizing the makespan.
Yoshiyuki KARUNO, Kento FURUKAWA
doaj   +1 more source

Teaching learning based optimization algorithm: and its engineering applications

, 2016
Describing a new optimization algorithm, the “Teaching-Learning-Based Optimization (TLBO),” in a clear and lucid style, this book maximizes reader insights into how the TLBO algorithm can be used to solve continuous and discrete optimization problems ...
Rao, R Venkata
core   +1 more source