Results 41 to 50 of about 369,296 (265)

Dynamic Programming Algorithms with Data Rounding for Combinatorial Food Packing Problems

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
The lexicographic bi-criteria combinatorial food packing problem to be discussed in this paper is described as follows. Given a set I = {i | i = 1, 2, . . .
Yoshiyuki KARUNO, Kazushi TAKAHASHI, Atsushi YAMADA   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Simultaneous Optimization of Variable Blank Holder Force Trajectory and Tools Motion in Deep Drawing via Sequential Approximate Optimization

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
In this paper, variable blank holder force (VBHF) trajectory and tools motion are optimized simultaneous by a sequential approximate optimization (SAO) with radial basis function (RBF) network.
Jirasak SRIRAT, Satoshi KITAYAMA, Koetsu YAMAZAKI   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Microfluidically frequency-reconfigurable compact self-quadruplexing tunable antenna with high isolation based on substrate integrated waveguide

Scientific Reports
This communication presents a novel concept of microfluidically frequency-reconfigurable self-quadruplexing tunable antenna for quad-band applications. At the initial design stage, a substrate-integrated square cavity is divided into four unequal quarter-
Rusan Kumar Barik, Slawomir Koziel
doaj   +1 more source

Compact design of a redundant manipulator system and application to multiple-goal tasks with temporal constraint

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2017
This paper aims to design a compact manipulator system consisting of a 6 degree-of-freedom (dof) manipulator and a 1-dof rotary table. It proposes a new compactness measure that considers manipulator swept volume or the space occupied by the system while
Lounell Bahoy GUETA, Ryosuke CHIBA, Tamio ARAI, Tsuyoshi UEYAMA, Jose Ildefonso Udang RUBRICO, Jun OTA   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Heuristic algorithms for a delivery workload balancing problem in an assembly plant

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
In this paper, a delivery workload balancing problem in an assembly plant is considered. The problem is first described as a special case of the unrelated parallel machine scheduling problem of minimizing the makespan.
Yoshiyuki KARUNO, Kento FURUKAWA
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source