Results 61 to 70 of about 160,456 (265)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Scientific ReportsThis communication presents a novel concept of microfluidically frequency-reconfigurable self-quadruplexing tunable antenna for quad-band applications. At the initial design stage, a substrate-integrated square cavity is divided into four unequal quarter-
Rusan Kumar Barik, Slawomir Koziel
doaj +1 more source
BiomimeticsThe secretary bird optimization algorithm is a recently developed swarm intelligence method with potential for solving nonlinear and complex optimization problems.
Changzu Chen +4 more
doaj +1 more source
Algorithm Engineering in Robust Optimization [PDF]
, 2016 Robust optimization is a young and emerging field of research having received a considerable increase of interest over the last decade. In this paper, we argue that the the algorithm engineering methodology fits very well to the field of robust optimization and yields a rewarding new perspective on both the current state of research and open research ...
Marc Goerigk, Anita Schöbel
openaire +2 more sources
Application of the Flower Pollination Algorithm in Structural Engineering
, 2021 In the design of a structural system, the optimum values of design variables cannot be derived analytically. Structural engineering problems have various design constraints concerning structural security measures and practicability in production.
Yang, Xin-She +2 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Adaptive Population Learning EJaya Algorithm for Real-World Optimization Problems [PDF]
International Journal of Mathematical, Engineering and Management SciencesEJaya enhances the global exploration capability of the Jaya algorithm but still suffers from drawbacks such as local stagnation and slow convergence due to its single learning strategy and weak population maintenance. To address these issues, this paper
Sonal Deshwal, Sandeep Kumar Mogha
doaj +1 more source
In this article, a case study is analysed using an adaptation of a project scheduling problem with multitasking resource restrictions. The objective is to reduce the operational costs of an open-pit mining process that uses mobile surface equipment, by ...
Solano-Charris E.L. +2 more
core +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source