Results 81 to 90 of about 160,456 (265)

Electronic enclosure design using distributed particle swarm optimization

, 2013
This article proposes a method for designing electromagnetic compatibility shielding enclosures using a peer-to-peer based distributed optimization system based on a modified particle swarm optimization algorithm.
Lewis, Andrew, Scriven, Ian, Lu, Junwei
core   +1 more source

Bond graph analysis in robust engineering design [PDF]

, 2000
Within engineering design, optimization often involves building models of working systems to improve design objectives such as performance, reliability and cost.
GABBRIELLI R., de Mast, J., Does, R.J.M.M., BRAGLIA, MARCELLO, van den Heuvel, E.R., BRAGLIA M., Heuvel, van den, E.R., Bates, RA, YANG, Zhenlin, BEVILACQUA M., Atherton, MA, GABBRIELLI, ROBERTO, Bates, R. A., Yang, Z., Schippers, W.A.J., Atherton, M. A., Mast, de, J., Does, R.J.M.M.; id_orcid, BEVILACQUA, MAURIZIO, Wu, Shuo-jye; Tsai, Tzong-ru, Xie, M., Gaudoin, O., Wu, Shuo-jye   +22 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

EDECO: An Enhanced Educational Competition Optimizer for Numerical Optimization Problems

Biomimetics
The Educational Competition Optimizer (ECO) is a newly proposed human-based metaheuristic algorithm. It derives from the phenomenon of educational competition in society with good performance.
Wenkai Tang, Shangqing Shi, Zengtong Lu, Mengying Lin, Hao Cheng   +4 more
doaj   +1 more source

Artificial rabbits optimization: A new bio-inspired meta-heuristic algorithm for solving engineering optimization problems

, 2022
In this paper, a new bio-inspired meta-heuristic algorithm, named artificial rabbits optimization (ARO), is proposed and tested comprehensively. The inspiration of the ARO algorithm is the survival strategies of rabbits in nature, including detour ...
Mirjalili, S, Cao, Q, Wang, L, Zhao, W, Zhang, Z   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Simultaneous optimization in plastic injection molding for weldline temperature and clamping force

Nihon Kikai Gakkai ronbunshu, 2017
In plastic injection molding (PIM), the process parameters such as melt temperature, mold temperature, injection time, and so on strongly affect the energy consumption as well as the product quality.
Kanako TAMADA, Satoshi KITAYAMA, Masahiro TAKANO, Shuji AIBA   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Optimization of energy distribution in hydraulic hammer forging considering billet jumping based on the three actuals

Journal of Advanced Mechanical Design, Systems, and Manufacturing
This paper presents an optimization of energy distribution in hydraulic hammer forging based on the three actuals which are (1) actual place, (2) actual product and (3) actual situation. For the automation in the hydraulic hammer forging, “billet jumping”
Satoshi KITAYAMA, Yasunari KAWAYACHI, Masaharu AMANO, Shuhei KONDO, Eri AONO   +4 more
doaj   +1 more source