Results 111 to 120 of about 784,364 (310)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Information, Competencies and Collaborative Teaching/Learning [PDF]

, 2002
The purpose of this paper is to survey the literature about current trends on several issues concerning technical information education including: 1. Information needs, user behaviors, access and availability of engineering information resources.
Osorio, Nestor L.
core  

Preface of the 6th Conference on Emerging Materials Processes

Materials Proceedings
The 6th Conference on Emerging Materials and Processes (CEMP 2023) was held on 22–23 November 2023, at the School of Chemical and Materials Engineering (SCME), National University of Sciences and Technology (NUST), Islamabad, Pakistan “https://cemp [...]
Sofia Javed, Waheed Miran, Erum Pervaiz, Iftikhar Ahmad   +3 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Characterization and Performance Evaluation of Magnesium Chloride-Enriched Polyurethane Nanofiber Patches for Wound Dressings

International Journal of Nanomedicine
Mohan Prasath Mani,1,2 Hemanth Ponnambalath Mohanadas,3 Ahmad Athif Mohd Faudzi,4,5 Ahmad Fauzi Ismail,6 Nick Tucker,7 Shahrol Mohamaddan,8 Manikandan Ayyar,9 Tamilselvam Palanisamy,1 Rajasekar Rathanasamy,10 Saravana Kumar Jaganathan11– 13 1Department ...
Mani MP, Ponnambalath Mohanadas H, Mohd Faudzi AA, Ismail AF, Tucker N, Mohamaddan S, Ayyar M, Palanisamy T, Rathanasamy R, Jaganathan SK   +9 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Multidisciplinarity and creativity of engineering and science students [PDF]

, 2017
Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2017.Cataloged from PDF version of thesis.Includes bibliographical references (pages 57-61).Engineering students must be prepared develop creative solutions to ...
Oki, Kristi Elena
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

A study of polyethylene oxide-polysiloxane networks as biomaterials for drug release [PDF]

, 1989
Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1989.Includes bibliographical references.by Cynthia Sung.Ph ...
Sung, Cynthia
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