Results 221 to 230 of about 4,806,683 (407)

England und die Englander [PDF]

Bulletin of the American Geographical Society, 1905
openaire   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

From aspiration to reality: a cross-country analysis of the implementation of lung cancer screening in Europe. [PDF]

Front Public Health
Poon C, Martinez Zamora A, Wilsdon T, Hartevelt M, Papin A.   +4 more
europepmc   +1 more source

Separating manifolds in slow-fast systems [PDF]

, 2005
England, James, Osinga, HM
core  

The changed role of the lender of last resort: Crisis responses of the Federal Reserve, European Central Bank and Bank of England

, 2013
Gayane Oganesyan
openalex   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Trends in dental procedures in England and Wales: A decade of ecological analysis. [PDF]

Medicine (Baltimore)
Alsaif MI, Bin Rahmah AS, Alamri H, Alsayed HD, Naser AY.   +4 more
europepmc   +1 more source

Forty lashes: The comparison of court punishments in early modern England and colonial Virginia

, 2014
Renee Therese Celeste
openalex   +1 more source

Straw use and availability for second generation biofuels in England

, 2013
N.J. Glithero, Paul N. Wilson, Stephen J. Ramsden   +2 more
openalex   +1 more source