Results 231 to 240 of about 4,724,242 (392)

Commentaries on the Laws of England

Journal of Legal History, 2019
Ian Williams
semanticscholar   +1 more source

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

Advanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang, Jian Qi, Jialiang Wang, Zhipeng Wang, Yongguang Wang, Zongtao Hu, Ao Xu, Bo Hong, Hongzhi Wang   +8 more
wiley   +1 more source

Adult extracorporeal cardiopulmonary resuscitation in the United Kingdom 2012 to 2022: A multicentre observational study. [PDF]

J Intensive Care Soc
Akhtar W, Galiatsou E, Pinto S, Brain N, Garcia M, Govier M, Finney S, Patel S, Pauli H, Raitt J, Richardson C, Rubino A, Sampson C, Scanlon C, Scott I, Barrett N, Vuylsteke A, Sherren P, Singer B, Camporota L, Patel B, Rosenberg A.   +21 more
europepmc   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

The BrainWaves study of adolescent wellbeing and mental health: Methods development and pilot data. [PDF]

PLoS One
Parsons RD, Bauermeister S, Turner J, Coles N, Thompson S, Squires E, Riseborough T, Bauermeister J, Simpkin A, French N, Cragg S, Lockhart-Jones H, Robertson O, Adlakha A, Thompson I, Gallacher J.   +15 more
europepmc   +1 more source

Are senior nurses on Clinical Commissioning Groups in England inadvertently supporting the devaluation of their profession?: A critical integrative review of the literature [PDF]

, 2016
Helen Allan, Roz Dixon, Gay Lee, Mike O’Driscoll, Jan Savage, Christine Tapson   +5 more
openalex   +1 more source

Equal Employment Opportunity Commission v. Eaglepicher, Inc. (f/k/a Eagle-Picher Industries, Inc.) [PDF]

, 2003
England, Judge James C.
core   +1 more source

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

Advanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu, Wanyi Zhao, Xinyu Chen, Yanzhou Wang, Shuoshuo Wei, Bo Xiang, Yingzhou Shi, Zongyue Li, Yangyang Yao, Jin Xie, Renyuan Qiu, Meng Shu, Shuo Xu, Ping Chen, Zhiying Chen, Yingjie Wu, Weibo Xia, Ling Gao, Yongfeng Song, Jiajun Zhao, Chao Xu   +20 more
wiley   +1 more source

Assessing land use change and the impacts on semi-natural habitats across England and Wales using four time points between 1930 and 2020. [PDF]

Landsc Ecol
Ridding LE, Wickenden AR, Orsler Z, Rowland CS, Hampton JM, Mitchell B, Edwardes A, Mullin K, Haughton G, Thurston N, Pola I, Sinclair G, Sinclair MR, Shaw J, Pywell RF.   +14 more
europepmc   +1 more source

A Field‐Deployable RotEx‐LAMP‐LFA Platform for Molecular Triage of HPV‐Driven Oncogenesis

Advanced Science, EarlyView.
This study presents RotEx‐LAMP‐LFA, a fully integrated, battery‐powered, low‐cost point‐of‐care device for rapid cervical cancer risk detection based on HPV16/18 E6/E7 mRNA. Clinically validated, the system demonstrated high sensitivity and specificity, and showed full concordance between self‐collected and clinician‐collected samples, offering a ...
Yuan Gao, Qiang Wen, Siyuan Qiao, Linyi Deng, Keyue Li, Zhuyan Shao, Xiaonan Liu, Tao Zhu, Chao Zhang, Da Han, Weihong Tan   +10 more
wiley   +1 more source