Results 51 to 60 of about 5,679,117 (300)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Advanced methods for enhanced sensing in biomedical Raman spectroscopy [PDF]
, 2015 Raman spectroscopy is a powerful tool in the field of biomedicine for disease diagnosis owing to its potential to provide the molecular fingerprint of biological samples.
Balagopal, Bavishna
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Evaluation of Choroidal Thickness in Normal Eyes Using Enhanced Depth Optical Coherence Tomography
Delhi Journal of Ophthalmology, 2017 Purpose: To evaluate the choroidal thickness in normal Indian population and to determine its correlation with age and refractive error Design: Cross sectional study conducted at a tertiary eye hospital in North India.
Harish +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Medicine Science, 2018 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Optic neuritis (ON) is common clinical manifestation of MS. Spectral domain optical coherence tomography (SD-OCT) has been used as a useful tool to quantify the neuronal ...
Serkan Akkaya +3 more
doaj +1 more source
Optical Coherence Tomography in Inflammatory and Neoplastic Lesions Deforming the Choroidal Profile
Diagnostics, 2023 The choroid is the main part of the uvea, the vascular layer of the eye that lies between the retina and the sclera. The high vascular component of the choroid makes this structure susceptible to inflammation in multisystemic diseases, as well as the ...
Elena Bolletta +8 more
doaj +1 more source
Extending AMCW lidar depth-of-field using a coded aperture [PDF]
, 2011 By augmenting a high resolution full-field Amplitude Modulated Continuous Wave lidar system with a coded aperture, we show that depth-of-field can be extended using explicit, albeit blurred, range data to determine PSF scale. Because complex domain range-
Michael J. Cree +5 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
View synthesis for depth from motion 3D x-ray imaging. [PDF]
, 2009 The depth from motion or kinetic depth X-ray imaging (KDEX) technique is designed to enhance the luggage screening at airport checkpoints. The technique requires multiple views of the luggage to be obtained from an arrangement of linear X-ray detector ...
Liu, Y
core