Results 31 to 40 of about 761,191 (268)
Metabolic engineering to enhance bacterial hydrogen production [PDF]
Microbial Biotechnology, 2007 Summary Hydrogen fuel is renewable, efficient and clean, and fermentative bacteria hold great promise for its generation. Here we use the isogenic Escherichia coli K‐12 KEIO library to rapidly construct multiple, precise deletions in the E. coli
Maeda, Toshinari +2 more
openaire +2 more sources
Fueling the Revolution: Targeting Metabolism to Enhance Immunotherapy
Cancer Immunology Research, 2021 AbstractThe success of immune-checkpoint blockade and chimeric antigen receptor (CAR) T cell therapies has established the remarkable capacity of the immune system to fight cancer. Over the past several years, it has become clear that immune cell responses to cancer are critically dependent upon metabolic programs that are specific to both immune cell ...
Robert D. Leone, Jonathan D. Powell
openaire +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Redox modulation and non-invasive evaluation of phenotypic adaptation of Escherichia coli Biofilm
International Journal of Electrochemical Science, 2010 Redox condition is a critical determinant of the metabolism of microbial biofilm. In this study, redox control of Escherichia coli biofilm adaptation in anaerobic chamber of electrochemical quartz crystal microbalance was performed to investigate the ...
Xuan-Hui Xie, Erin Lin Li, Zi Kang Tang
doaj +1 more source
Assays to enhance metabolic phenotyping in the kidney
American Journal of Physiology-Renal PhysiologyWe show significant metabolic differences between both primary and immortalized cells, and among primary cells with different durations in cell culture. In addition, 3H-palmitate oxidation in tissue ex vivo is described as a method novel to the kidney for assessing the complete oxidation of long-chain fatty acids.
Safaa Hammoud +7 more
openaire +2 more sources
Methylene Blue as a Cerebral Metabolic and Hemodynamic Enhancer
PLoS ONE, 2012 By restoring mitochondrial function, methylene blue (MB) is an effective neuroprotectant in many neurological disorders (e.g., Parkinson's and Alzheimer's diseases). MB has also been proposed as a brain metabolic enhancer because of its action on mitochondrial cytochrome c oxidase.
Ai-Ling Lin +10 more
openaire +4 more sources
Enhancement of folates in plants through metabolic engineering [PDF]
Proceedings of the National Academy of Sciences, 2004 Humans depend on plants as a major source of dietary folates. Inadequate dietary levels of the vitamin folate can lead to megaloblastic anemia, birth defects, impaired cognitive development, and increased risk of cardiovascular disease and cancer.
Tahzeeba, Hossain +5 more
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Dihydromyricetin Protects the Liver via Changes in Lipid Metabolism and Enhanced Ethanol Metabolism [PDF]
Alcoholism: Clinical and Experimental Research, 2020 BackgroundExcess alcohol (ethanol, EtOH) consumption is a significant cause of chronic liver disease, accounting for nearly half of the cirrhosis‐associated deaths in the United States. EtOH‐induced liver toxicity is linked to EtOH metabolism and its associated increase in proinflammatory cytokines, oxidative stress, and the subsequent activation of ...
Joshua Silva +8 more
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source