Results 71 to 80 of about 761,191 (268)

Differential regulation of rice seedling morphogenesis, carbon metabolism, and energy charge by Pro-Ca and GA₃ under salt stress

BMC Plant Biology
Background This study explored the pivotal role of exogenous plant growth regulators in enhancing salt tolerance in rice. The underlying regulatory mechanisms of gibberellin (GA₃) and prohexadione-calcium (Pro-Ca) under NaCl stress remain unclear.
Qicheng Zhang, Jiangyuan Ya, Aaqil Khan, Shaobiao Duan, Wenkang Huang, Rui Deng, Jianqin Zhang, Zhiyuan Sun, Naijie Feng, Dianfeng Zheng, Mehnaz Bano   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

ALS gene overexpression and enhanced metabolism conferring Digitaria sanguinalis resistance to nicosulfuron in China. [PDF]

Front Plant Sci, 2023
Wang R, Sun Y, Lan Y, Wei S, Huang H, Li X, Huang Z.   +6 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The Photorespiratory BOU Gene Mutation Alters Sulfur Assimilation and Its Crosstalk With Carbon and Nitrogen Metabolism in Arabidopsis thaliana

Frontiers in Plant Science, 2018
This study was aimed at elucidating the significance of photorespiratory serine (Ser) production for cysteine (Cys) biosynthesis. For this purpose, sulfur (S) metabolism and its crosstalk with nitrogen (N) and carbon (C) metabolism were analyzed in ...
Sladjana Samuilov, Dominik Brilhaus, Nadine Rademacher, Samantha Flachbart, Leila Arab, Saleh Alfarraj, Franziska Kuhnert, Stanislav Kopriva, Andreas P. M. Weber, Tabea Mettler-Altmann, Heinz Rennenberg, Heinz Rennenberg   +11 more
doaj   +1 more source

Cytochrome P450s-Involved Enhanced Metabolism Contributes to the High Level of Nicosulfuron Resistance in Digitaria sanguinalis from China. [PDF]

Biology (Basel), 2023
Wang X, Hu W, Li Y, Jiang M, Zhao N, Cao H, Liao M.   +6 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

An Asp376Glu substitution in ALS gene and enhanced metabolism confers high tribenuron-methyl resistance in Sinapis alba. [PDF]

Front Plant Sci, 2022
Palma-Bautista C, Vázquez-García JG, Osuna MD, Garcia-Garcia B, Torra J, Portugal J, De Prado R.   +6 more
europepmc   +1 more source

Correlation-enhanced viable core in metabolic networks

Chaos, Solitons & Fractals
Cellular ingredient concentrations can be stabilized by adjusting generation and consumption rates through multiple pathways. To explore the portion of cellular metabolism equipped with multiple pathways, we categorize individual metabolic reactions and compounds as viable or inviable: A compound is viable if processed by two or more reactions, and a ...
Mi Jin Lee, Sudo Yi, Deok-Sun Lee
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source