Results 91 to 100 of about 592,714 (262)

ORMOSIL Coatings Enriched with CeO₂ (5-ATDT)-Ceramic Nanocontainers for Enhanced Protection of HDG Steel Used in Concrete. [PDF]

Materials (Basel), 2022
Kordas G.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

PERSEUS: Protection-Enhanced Resilient System for Securing Ubiquitous Healthcare Solutions

Applied Sciences
The increasing use of medical applications using mobile devices has led to increased concerns about data security. Mobile Edge Computing (MEC) is an emerging technology that can be used to improve end-user services, especially in medical applications ...
Miguel Landry Foko Sindjoung, Garrik Brel Jagho Mdemaya, Martinien Deffo Foko, Mthulisi Velempini   +3 more
doaj   +1 more source

DNA Prime and Recombinant Protein Boost Vaccination Confers Chickens with Enhanced Protection against Chicken Infectious Anemia Virus. [PDF]

Viruses, 2022
Liu L, Yin M, Li Y, Su H, Fang L, Sun X, Chang S, Zhao P, Wang Y.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Acute Inflammation Confers Enhanced Protection against Mycobacterium tuberculosis Infection in Mice. [PDF]

Microbiol Spectr, 2021
Piergallini TJ, Scordo JM, Pino PA, Schlesinger LS, Torrelles JB, Turner J.   +5 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Recombinant BCG-Prime and DNA-Boost Immunization Confers Mice with Enhanced Protection against Mycobacterium kansasii. [PDF]

Vaccines (Basel), 2021
Komine-Aizawa S, Mizuno S, Matsuo K, Namiki T, Hayakawa S, Honda M.   +5 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MEC Placement Problem in Protected 5G Networks

CLEI Electronic Journal
This paper summarizes the thesis ”MEC Placement Problem in Protected 5G Networks”, which tackles the question of where to position Multi-access edge computing nodes (MECs) in 5G networks to achieve stringent 5G requirements at a minimum cost. The thesis
Hernani Delgado Chantre
doaj   +1 more source