Results 81 to 90 of about 1,780,158 (303)

Extended Capabilities for a Privacy-Enhanced Participatory Sensing Infrastructure (PEPSI)

, 2013
Participatory sensing is emerging as an innovative computing paradigm that targets the ubiquity of always-connected mobile phones and their sensing capabilities.
De Cristofaro, Emiliano, Soriente, Claudio   +1 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

N-Acetylcysteine–Enhanced Contrast Provides Cardiorenal Protection

JACC: Cardiovascular Interventions, 2009
We sought to evaluate the cardiac and renal effects of an N-acetylcysteine (NAC)-enhanced intracoronary radiographic contrast agent.Recent studies suggest that high-dose NAC provides better protection from contrast-induced nephropathy, and the antioxidant properties of NAC may also provide cardiac protection.
Meyer, Markus, LeWinter, Martin M., Bell, Stephen P., Chen, Zengyi, Selby, Donald E., Singla, Dinender K., Dauerman, Harold L.   +6 more
openaire   +2 more sources

Sequential Innovation, Patents, and Imitation [PDF]

We argue that when discoveries are "sequential" (so that each successive invention builds in an essential way on its predecessors) patent protection is not as useful for encouraging innovation as in a static setting.
Eric Maskin, James Bessen
core  

Chlamydia trachomatis and Chlamydophila abortus induce the expression of secretory leukocyte protease inhibitor in cells of the human female reproductive tract [PDF]

, 2008
C. trachomatis and C. abortus are related Gram-negative intracellular bacteria that cause reproductive failure due to infertility (C. trachomatis) or abortion (C. abortus). These organisms target epithelial cells in the reproductive tract and/or placenta,
Entrican, Gary, Fitch, Paul, Fleming, Diana, Kelly, Rodney, Wattegedera, Sean, Wheelhouse, Nick   +5 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Design of F-ZIF-67/PDMS-based triboelectric nanogenerator for enhanced cathodic protection

npj Materials Degradation
Metal corrosion poses significant economic and safety challenges across industries, necessitating efficient cathodic protection strategies. Triboelectric nanogenerator (TENG) offers a promising self-powered solution by harvesting ambient mechanical ...
Tengfei Xiang, Xuxin Chen, Jihuai Wang, Di Liu, Linjing Cui, Tao Wang, Zhenya Zhang, Yang Yang, Shihong Zhang   +8 more
doaj   +1 more source

The Economics of Content Protection [PDF]

In a model that allows smooth substitution between domestic and imported inputs, content protection distorts inout choice but does not force a divergence between price and unit production cost.
Michael L. Mussa
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Highly Efficient Photo-Induced Cathodic Protection of 403SS by the All-Solid-State Z-Scheme ZnS-CdS-Ag@TiO2 Nanoheterojunctions

International Journal of Electrochemical Science, 2019
An all-solid-state Z-scheme ZnS-CdS-Ag@TiO2 nanoheterojunction was successfully fabricated to reduce the recombination rate of photogenerated charge carriers and enhance the photocathodic protection efficiency for 403 stainless steel (SS).
Yanfeng Zhu, Yuanwei Liu, Zhongnian Yang
doaj   +1 more source