Results 71 to 80 of about 1,780,158 (303)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Can Food Processing Enhance Cancer Protection? [PDF]

Nutrition Today, 2014
Food processing can be defined as the transformation of raw ingredients into food or of food into other forms. This review summarizes an American Institute for Cancer Research symposium that addressed the question of what is known about food processing in relation to cancer risk.
John W, Erdman, Elizabeth, Jeffery, Marc, Hendrickx, Amanda J, Cross, Johanna W, Lampe   +4 more
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Disulfide-stabilized trimeric hemagglutinin ectodomains provide enhanced heterologous influenza protection

Emerging Microbes and Infections
Influenza virus infection poses a continual menace to public health. Here, we developed soluble trimeric HA ectodomain vaccines by establishing interprotomer disulfide bonds in the stem region, which effectively preserve the native antigenicity of stem ...
De-Jian Liu, Xiu-Qin Zhong, Yan-Xia Ru, Shi-Long Zhao, Cui-Cui Liu, Yi-Bo Tang, Xuan Wu, Yi-Shuai Zhang, Hui-Hui Zhang, Jia-Yue She, Mu-Yang Wan, Yao-Wang Li, He-Ping Zheng, Lei Deng   +13 more
doaj   +1 more source

Rateless Polar-Spinal Coding Scheme With Enhanced Information Unequal Error Protection

IEEE Access, 2019
In this paper, a rateless coding scheme with enhanced unequal error protection (UEP) property is proposed by concatenating the systematic polar code (SPC) and spinal code, where SPC is used as the outer code and spinal code is the inner code.
Hao Liang, Aijun Liu, Fengyi Cheng, Xiaohu Liang   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Welfare Effects of Employment Protection [PDF]

Employment protection is often related to costs incurred by the firms when they hire a worker.The stability of the employment relationship, enhanced by employment protection, is also favorable to the productivity of the job.We analyze employment ...
Belot, M.V.K., Boone, J., Ours, J.C. van
core   +1 more source

Thermal Degradation of Blends of Polystyrene and poly(sodium 4-styrenesulfonate) and the copolymer, poly(styrene-co-sodium 4-styrenesulfonate) [PDF]

, 1999
The thermal degradation of blends and copolymers of styrene with styrenesulfonic acid has been studied using thermogravimetric analysis, TGA/FTIR, and cone calorimetry.
Wilkie, Charles, Yao, Qiang
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Towards a synthesis of multimedia and intelligent tutoring systems : a dissertation presented in partial fulfilment of the requirements for the degree of Master of Science in Computer Science at Massey University [PDF]

, 1998
Multimedia is being used in almost every field. This study is about the use of multimedia in the area of intelligent tutoring systems. This project studies the advantages and disadvantages of interactive multimedia and intelligent tutoring systems, and ...
Vethanayagam, Emma A. K
core