Results 71 to 80 of about 627,492 (310)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Enhanced Inspection and Maintenance (I/M) Program for the State of New Jersey, Revised Performance Standard Modeling

open access: yes, 2002
This document is a revision to the State of New Jersey's enhanced inspection and maintenance (I/M) program State Implementation Plan (SIP). Specifically, this document provides the United States Environmental Protection Agency (USEPA) with a revision to ...

core   +1 more source

Thermal Protection Performances of the Macro and/or Nano Enhanced PCM in a Representative Battery Pack

open access: yes, 2022
This experimental study focused on the comparison of thermal protection performances of macro and/or nano enhanced organic PCM in a representative battery pack from low to high discharge rates.
Temel, Ümit Nazlı; Kılınç, Ferhat; Coşkun, Serkan
core   +1 more source

Enhancing the Protective Immune Response against Botulism [PDF]

open access: yesInfection and Immunity, 2013
ABSTRACTThe need for a vaccine against botulism has increased since the discontinuation of the pentavalent (ABCDE) botulinum toxoid vaccine by the Centers for Disease Control and Prevention. The botulinum toxins (BoNTs) are the primary virulence factors and vaccine components against botulism.
Amanda, Przedpelski   +6 more
openaire   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Disulfide-stabilized trimeric hemagglutinin ectodomains provide enhanced heterologous influenza protection

open access: yesEmerging Microbes and Infections
Influenza virus infection poses a continual menace to public health. Here, we developed soluble trimeric HA ectodomain vaccines by establishing interprotomer disulfide bonds in the stem region, which effectively preserve the native antigenicity of stem ...
De-Jian Liu   +13 more
doaj   +1 more source

Rateless Polar-Spinal Coding Scheme With Enhanced Information Unequal Error Protection

open access: yesIEEE Access, 2019
In this paper, a rateless coding scheme with enhanced unequal error protection (UEP) property is proposed by concatenating the systematic polar code (SPC) and spinal code, where SPC is used as the outer code and spinal code is the inner code.
Hao Liang   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Surface-enhanced Raman spectroscopy using silver impregnated polycarbonate substrates [PDF]

open access: yes, 2007
Novel substrates based on noble metal nanoparticles are currently the subject of extensive research in fields such as biological sensing, medicine, spectroscopy and nano-photonics due to the large electromagnetic fields generated in the vicinity of the ...
Peacock, A.C.   +11 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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