Results 111 to 120 of about 1,693,537 (318)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

HUMANITY'S END: WHY WE SHOULD REJECT RADICAL ENHANCEMENT

open access: yes, 2010
Acknowledgments -- 1. What is radical enhancement? -- 2. Radical enhancement and posthumanity -- 3. The technologist: Ray Kurzweil and the law of accelerating returns -- 4. Is uploading ourselves into machines a good bet? -- 5. The therapist: Aubrey
Agar, Nicholas
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

وَسَائِلُ الإثبَاتِ المُعَاصِرَة لِتَوثِيقِ العُقُود/ دِرَاسَةٌ فِقهِيَّةٌ مُقَارَنَةٌ

open access: yesمجلة كلية العلوم الأسلامية
Documentation is crucial in people's lives because of the natural human inclination towards ownership and wealth accumulation. This desire can lead to conflicts with others' interests, potentially resulting in disputes that may involve actions prohibited
يوسف نوري حمه باقي
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Medical image enhancement using threshold decomposition driven adaptive morphological filter [PDF]

open access: yes, 2008
One of the most common degradations in medical images is their poor contrast quality. This suggests the use of contrast enhancement methods as an attempt to modify the intensity distribution of the image.
Mahmoud, Tarek A.   +4 more
core   +1 more source

Heat Treatment of Calcite to Enhance Its Removal of Color Dye Alizarin Red S

open access: yesCrystals
The use of color dyes in modern society presents a great challenge to the environment. Thus, extensive studies have been conducted in the last 30 years on the removal of color dyes from aqueous solutions such industrial wastewater.
Zhaohui Li   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A GPU-Accelerated Adaptive Simultaneous Dynamic Range Compression and Local Contrast Enhancement Algorithm for Real-Time Color Image Enhancement

open access: yes, 2017
Dynamic range compression is an important function used in modern digital video cameras and displays to improve visual quality of standard dynamic range color images.
Chi-Yi Tsai; Chih-Hung Huang
core   +1 more source

Accuracy Enhancement of ASTER Global Digital Elevation Models Using ICESat Data

open access: yesRemote Sensing, 2011
Global Digital Elevation Models (GDEM) are considered very attractive for current research and application areas due to their free and wide range accessibility.
Peter Reinartz, Hossein Arefi
doaj   +1 more source

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