Results 121 to 130 of about 1,693,537 (318)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Coquille River instream enhancement project #201-466

open access: yes, 2005
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Oct.

core  

Image Enhancement Thanks to Negative Grey Levels in the Logarithmic Image Processing Framework

open access: yesSensors
The present study deals with image enhancement, which is a very common problem in image processing. This issue has been addressed in multiple works with different methods, most with the sole purpose of improving the perceived quality.
Michel Jourlin
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

https://www.scienzaefilosofia.com/2024/07/18/morale-e-tecnica-il-caso-del-potenziamento-umano/ [PDF]

open access: yesS&F_scienzaefilosofia.it
Morality and technology. The case of human enhancement The purpose of this paper is to probe the moral implications of human enhancements. According to a generally accepted thesis, enhancements are not only morally neutral, but a number of ...
ADORNO, FRANCESCO PAOLO
doaj  

Super Enhancers [PDF]

open access: yesCirculation Research, 2020
Timothy J. Cashman, Chinmay M. Trivedi
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Oregon watershed assessment manual

open access: yes, 1999
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes."Developed for the Governor's Watershed Enhancement Board ...

core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Governor's Watershed Enhancement Board

open access: yes, 1991
An overview of the efforts to improve the quality of Oregon's watersheds.produced by Allied Video Productions.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

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