Results 291 to 300 of about 8,934,200 (403)

ENHANCE and ONTARGET [PDF]

Preventive Cardiology, 2008
openaire   +3 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Single-cell Micro-C profiles 3D genome structures at high resolution and characterizes multi-enhancer hubs. [PDF]

Nat Genet
Wu H, Zhang J, Tan L, Xie XS.
europepmc   +1 more source

Gibberellin-Enhanced CO₂ Release from Tryptophan-1-C-14 in Plant Apical Tissue

, 1966
Jack G. Valdovinos, Leland C. Ernest
openalex   +2 more sources

Modification of enhancer chromatin: what, how, and why?

Molecules and Cells, 2013
Eliezer Calo, J. Wysocka
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Ligand-specific regulation of a binary enhancer code dictating cellular senescence. [PDF]

Proc Natl Acad Sci U S A
Suter T, Friedman MJ, Tazearslan C, Merkurjev D, Ohgi K, Meluzzi D, Rosenfeld MG, Suh Y.   +7 more
europepmc   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Functional characterization of transcriptional enhancers in an Anopheles genetic locus controlling natural resistance to the malaria parasite, Plasmodium falciparum. [PDF]

Epigenetics Chromatin
Zmarlak-Feher NM, Taquet KS, Zakhia R, Pain A, Brito-Fravallo E, Anderson CE, Vernick KD, Mitri C, Riehle MM.   +8 more
europepmc   +1 more source

KLF4 is involved in the organization and regulation of pluripotency-associated three-dimensional enhancer networks

Nature Cell Biology, 2019
D. C. Di Giammartino, A. Kloetgen, A. Polyzos, Yiyuan Liu, Daleum Kim, Dylan Murphy, Abderhman Abuhashem, Paola Cavaliere, B. Aronson, Veevek Shah, Noah E. Dephoure, M. Stadtfeld, A. Tsirigos, E. Apostolou   +13 more
semanticscholar   +1 more source