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Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers. [PDF]

open access: yesMil Med Res
Cai YM   +29 more
europepmc   +1 more source
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HIV TAR: An RNA enhancer?

Cell, 1989
Deux proteines du viurs HIV participent a la regulation de l'expression des genes de ce virus. Certains genes sont actives en trans par la proteine Tat ceci par l'intermediaire de l'element TAR, element qui se distingue des sites de liaison des facteurs de transcription typiques.
Phillip A Sharp
exaly   +3 more sources

RNA switch at enhancers

Nature Genetics, 2014
Polycomb/Trithorax response elements (PRE/TREs) are genetic elements that can stably silence or activate genes. A new study describes how long noncoding RNAs (lncRNAs) transcribed from opposite strands of the Drosophila melanogaster vestigial PRE/TRE throw the switch between these two opposing epigenetic states.
Jeffrey J, Quinn, Howard Y, Chang
openaire   +2 more sources

Enhancing the RNA engineering toolkit

Science, 2017
The CRISPR-Cas13 system can be used to engineer ...
Li, Yang, Ling-Ling, Chen
openaire   +2 more sources

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