Mass Spectrometry-based Structural Proteomics: Methodology and Application of Fast Photochemical Oxidation of Proteins (FPOP) [PDF]
The dissertation will be solely focused on using mass spectrometry to characterize protein high order structures (HOS), it emphasizes the use of hydroxyl radical footprinting (FPOP) coupled to bottom-up MS approach.
Niu, Ben
core +1 more source
Innate Immune Cell Regulation of Metabolic Homeostasis [PDF]
Obesity is an increasingly prevalent disease regulated by genetic and environmental factors. Emerging studies indicate that immune cells, including monocytes, granulocytes and lymphocytes, regulate metabolic homeostasis and are dysregulated in obesity ...
Brestoff, Jonathan
core +1 more source
Carbon turnover in the water-soluble protein of the adult human lens. [PDF]
PurposeHuman eye lenses contain cells that persist from embryonic development. These unique, highly specialized fiber cells located at the core (nucleus) of the lens undergo pseudo-apoptosis to become devoid of cell nuclei and most organelles. Ostensibly
Buchholz, Bruce A+7 more
core +1 more source
Prediction of Peptide Conformation by Multicanonical Algorithm: A New Approach to the Multiple-Minima Problem [PDF]
We apply a recently developed method, multicanonical algorithm, to the problem of tertiary structure prediction of peptides and proteins. As a simple example to test the effectiveness of the algorithm, Met-enkephalin is studied and the ergodicity problem, or multiple-minima problem, is shown to be overcome by this algorithm.
arxiv
Role of CD10 in the Metastasis of Colorectal Cancer to the Liver. [PDF]
CD10 is a widely expressed endopeptidase that is present in human colorectal cancer (CRC), which shows a high frequency of liver metastasis. CD10 expression in CRC cells is associated with liver metastasis in rodent models, and CD10 expression enhances ...
Fujii, Kiyomu+7 more
core
Augmentation of the natriuretic response to atrial natriuretic factor in cirrhosis [PDF]
Gerbes+6 more
core +1 more source
Biochemical and pharmacological studies of the metabolism of dynorphin 1-8 [PDF]
The metabolism of the opioid peptide [3H]dynorphin 1-8 by slices of central nervous system (c.n.s.) and peripheral tissues, from the rat and guinea-pig has been studied.
Diane M. Dixon (7167092)
core
ClickArr: a novel, high-throughput assay for evaluating β-arrestin isoform recruitment. [PDF]
French AR, Meqbil YJ, van Rijn RM.
europepmc +1 more source
Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core
Avian opioid peptides: evolutionary considerations, functional roles and a challenge to address critical questions. [PDF]
Pierzchała-Koziec K, Scanes CG.
europepmc +1 more source