Results 161 to 170 of about 110,810 (218)

Crystal structure of methionine-enkephalin

Biochemical and Biophysical Research Communications, 1986
The crystal structure of methionine-enkephalin has been determined by X-ray crystallography. There are two independent pentapeptides in the asymmetric unit and both display extended backbone conformations with their side chains arranged alternately below and above the backbone plane.
Norman Camerman, Arthur Camerman, Donald Mastropaolo   +2 more
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OCCURRENCE OF METHIONINE-ENKEPHALIN-ARG6-GLY⁷-LEU⁸WITH METHIONINE-ENKEPHALIN, LEUCINE-ENKEPHALIN AND METHIONINE-ENKEPHALIN-ARG6-PHE⁷IN HUMAN GASTRIC ANTRUM.

The Journal of Clinical Endocrinology & Metabolism, 1983
Recent studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin from bovine adrenal medulla and human pheochromocytoma have revealed that this precursor molecule contains four copies of methionine-enkephalin (Met-Enk) and one copy each of leucine-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg6-
Kosho Takasu, Yoshio Ikeda, Shinichiro Shimbo, Hiroo Imura, Kazuwa Nakao, Takaaki Yoshimasa, Noboru Yanaihara, Mitsuaki Suda, Makoto Sakamoto   +8 more
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Dopamine and methionine-enkephalin in human brain

Neuroscience Letters, 1982
Abstract The contents of dopamine (determined radioenzymatically) and methionine-enkephalin (assayed by a radioimmunoassay) were measured in several areas of the human brain. The peptide was principally localized in dopamine-rich structures. In patients with Parkinson's disease, in contrast to the general dopamine deficiency, the reduction in ...
Brigitte Berger, H. Taquet, François Cesselin, F. Javoy-Agid, A. Ploska, Yves Agid, M. Hamon, J.C. Legrand, Patricia Gaspar   +8 more
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ENZYME IMMUNOASSAY FOR METHIONINE‐ENKEPHALIN SULFOXIDE

Clinical and Experimental Pharmacology and Physiology, 1990
SUMMARY1. An immunoassay technique employing an enzyme‐labelled ligand was developed for the sulfoxide derivative of the opioid peptide methionine‐enkephalin (MOE).2. The sensitivity of the enzyme immunoassay (EIA) was approximately twofold higher than that achieved in the radio‐immunoassay (RIA) using tritiated ligand.
Jean E. Olley, George K. L. Tiong
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Totalsynthese von Methionin‐Enkephalin

Angewandte Chemie, 1976
Zwanzigfache Normorphin‐Wirkung zeigt das aus Schweinehirn isolierte Pentapeptid (1), das man infolgedessen auch als „endogenes Opiat”︁ bezeichnet hat. Jetzt wird die Totalsynthese dieses Stoffes beschrieben magnified image.
Wolfgang Voelter, Emanuel Pietrzik, Claus Bürvenich, Hans Horn, Hubert Kalbacher   +4 more
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Methionine Enkephalin: Clinical Pharmacology [PDF]

, 1986
Earlier studies indicated that methionine enkephalin infusions (1,000 micrograms) in normal volunteers induced facial flushing, general vasodilation and noisy stomach (borborgymi). Blood pressure and pulse rate were normal in all experiments. Plasma levels of pancreatic polypeptide, somatostatin, T3 and T4, TSH, FSH, PRL, ACTH, and GH were unchanged ...
R. Richter, J. L. Valentine, G. C. Miller, M. Fesen, Anthony J. Murgo, S. Solomon, L. Edwards, Robert E. Faith, N. P. Plotnikoff   +8 more
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Toward an Understanding of the Oxidation Process of Methionine Enkephalin: A Combined Electrochemistry, Quantum Chemistry and Quantum Chemical Topology Analysis.

Journal of Physical Chemistry B, 2015
Recent experimental results about the oxidation of methionine enkephalin by ·OH radicals indicated an intramolecular electron transfer between the C-terminal methionine radical cation and the tyrosine N-terminus too fast to be observed.
J. Bergès, A. Kamar, P. de Oliveira, J. Pilmé, E. Luppi, C. Houée-Levin   +5 more
semanticscholar   +1 more source

Synaptic mechanism of methionine-enkephalin uptake

Life Sciences, 1982
The actions of classical neurotransmitters at the synapse are rapidly terminated either by re-uptake or by enzymatic degradation. Enkephalins, like other neurotransmitters, have been demonstrated to be degraded by active proteinases present in the brain. However, it has been generally assumed that an uptake process is not operant for met-enkephalin. To
J. Go, I. Jamal, B.P. Roy
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Cross tolerance between morphine and methionine-enkephalin [PDF]

Nature, 1976
TOLERANCE and dependence are characteristic symptoms in man during prolonged use of opiates. We have pointed out1 that for an understanding of these phenomena the interaction between endogenous enkephalin and exogenous opiates is of importance. Normally, enkephalin can be assumed to control inhibitory mechanisms determining the rate of neurotransmitter
Hans W. Kosterlitz, Angela A. Waterfield, John Hughes   +2 more
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Influence of Ethanol Dependence and Methionine Enkephalin Antisense on Serum Endomorphin‐1 and Methionine Enkephalin Levels

Alcoholism: Clinical and Experimental Research, 2004
Abstract: Background: Opiate peptides are involved in the physical dependence on ethanol. Levels of methionine enkephalin (MEnk), for example, are affected by ethanol. No study on the effect of ethanol on endomorphin, the endogenous ligand for the μ‐opiate receptor, has yet been conducted.Methods: We examined the effect of ethanol ingestion on serum
John E. Morley, Vijaya B. Kumar, William A. Banks   +2 more
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